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Table 4 Statistical analysis of the proposed, official and the reported methods of CAR and IVA in their pure forms

From: A unique revolutionary eco-friendly spectrophotometric technique for solving the spectral overlap in the determination of carvedilol and ivabradine in their binary combination: stability study

Parameter

CAR

RD

FDW-SS

CC-SS

ITAD-RS

Official method*

Mean

99.38

98.45

99.88

SD

0.92

0.85

0.95

N

5

5

4

Variance

0.85

0.72

0.9

Student's t test*** (2.365)

0.796

2.352

 

F***

1.059 (9.120)

1.250 (6.590)

 

Parameter

IVA

RD

FDW-SS

CC-SS

ITAD-RS

Reported method**

Mean

99.47

99.15

99.6

SD

1.41

0.87

1.06

N

5

5

5

Variance

1.99

0.76

1.12

Student's t test*** (2.306)

0.165

0.734

 

F*** (6.390)

1.777

1.474

 
  1. *BP determination of carvedilol by official potentiometric method [1]
  2. **Derivative ratio spectrophotometric method [8] for determination of ivabradine
  3. ***The values in the parenthesis are the corresponding theoretical values of t and F at (p = 0.05). No significant difference by using one-way ANOVA with F equals 0.637 (Fcrit = 3.239) and p equals (0.602)