A unique revolutionary eco-friendly spectrophotometric technique for solving the spectral overlap in the determination of carvedilol and ivabradine in their binary combination: stability study

Future Journal of Pharmaceutical Sciences

Table 5 Greenness assessment of the proposed, official and the reported methods according to Eco-Scale, NEMI, GAPI and AGREE tools

Tool	Proposed	Official [1]	Reported [8]
Analytical Eco-scale
Water	0	–	–
Acetic acid	–	8	4
Perchloric acid	–	8	–
Energy Consumption	0	0	0
Occupational Hazard	0	0	0
Waste	3	5	3
Total Penalty Point	3	13	7
Eco-score	97	79	93
NEMI
GAPI Tool
AGREE Tool