Fig. 3From: Brentuximab vedotin resistance in classic Hodgkin's lymphoma and its therapeutic strategies: a reviewDifferent interactions of cell surface receptors of HRS cells with the tumor microenvironment describe the way the HRS cells influence the microenvironment. Such influence is the driving cause behind sustained tumor growth and unchecked proliferation. In the figure, we can see the CD30 binding eosinophils and mast cells and also interacting with mast cell-produced interleukinsBack to article page