Antidiarrhoeal screening of Himalayan edible plant Begonia rubrovenia and its marker followed by its validation using computational analysis

Future Journal of Pharmaceutical Sciences

Table 1 Effect of B. rubrovenia extract on normal faecal excretion rate

Treatment	Faecal wet weight (g) at various times (h) after treatment				Wet/dry weight of faeces
Treatment	1	3	5	7	Wet/dry weight of faeces
Normal Control	0.072 ± 0.003	0.328 ± 0.01	0.543 ± 0.02	0.905 ± 0.03	1.367 ± 0.05
EBV 100	0.379 ± 0.01^a	0.380 ± 0.01	0.691 ± 0.03^a	0.672 ± 0.03^a	1.233 ± 0.07
EBV 200	0.516 ± 0.02^a	0.542 ± 0.02^a	0.463 ± 0.02	0.394 ± 0.01^a	1.070 ± 0.04^a
EBV 300	0.525 ± 0.02^a	0.534 ± 0.02^a	0.442 ± 0.02^a	0.397 ± 0.01^a	1.099 ± 0.02^a
Quercetin	0.490 ± 0.02^a	0.529 ± 0.02^a	0.510 ± 0.02	0.470 ± 0.01^a	1.108 ± 0.03^a
Loperamide	0.451 ± 0.02^a	0.299 ± 0.01	0.234 ± 0.01^a	0.191 ± 0.007^a	1.058 ± 0.01^a

Values are mean ± S.E.M. (n = 6)
In table EBV Ethanolic extract of Begonia rubrovenia at dose level of 100, 200 and 300 mg/kg, p.o.
^ap < 0.05 vs. Normal
^bp < 0.05 vs. Castor oil