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Table 3 The Knowledge of PCPs in anticoagulant therapy for NVAF patients

From: Assessing physicians’ knowledge, attitude, and practice on anticoagulant therapy in non-valvular atrial fibrillation: Syrian insights

Knowledge of PCPs items

Frequency

Percentage%

How to diagnose AF

ECG

426

85.7

Holter

68

13.7

Auscultation of the heart and palpation of the pulse

3

0.6

Which score tool can be used to predict stroke risk in AF patients

CHADS2 score

63

12.7

CHADS2-VASc score

308

62

HAS-BLED score

6

1.2

ORBIT score

3

0.6

Not known

117

23.5

Which score tool can be used to predict bleed risk in AF patients

CHADS2 score

21

4.2

CHADS2-VASc score

35

7

HAS-BLED score

262

52.7

ORBIT score

15

3

Not known

164

33

What risk factors does the CHADS2 score include

Hypertension

353

71

Diabetes

315

63.4

Dyslipidemia

132

26.6

Congestive heart failure

280

56.3

Female

134

27

Age > 75yo

334

67.2

Prior stroke/TIA

274

55.1

Not known

88

17.7

What risk factors does the CHADS2-VASc score include

Diabetes

276

55.5

Prior stroke/TIA/thrombosis

320

64.4

Vascular disease

275

55.3

Age 65–74 yo

227

45.7

Age ≥ 75 yo

277

55.7

Hypertension

296

59.6

Congestive heart failure/left ventricular dysfunction

288

57.9

Female

208

41.9

Dyslipidemia

75

15.1

Not known

107

21.5

What risk factors does the HAS-BLED score include

Female

68

13.7

Hypertension

228

45.9

Liver dysfunction and renal dysfunction

228

45.9

Stroke

167

33.6

History of bleeding

255

51.3

Unstable INR

241

48.5

Alcoholism

161

32.4

Concomitant medications (eg. antiplatelet drugs, NSAIDS)

180

36.2

Age > 65yo

200

40.2

Not known

182

36.6

Which indicator should be monitored in AF patients with warfarin

PT

267

53.7

APTT

63

12.7

INR

415

83.5

D-Dimer

20

4

Fibrinogen

13

2.6

Not known

12

2.4

How long should be monitor coagulation function in AF patients with long-term warfarin therapy at a stable period?

Every 2 days

27

5.4

Every 7 days

99

19.9

Every 30 days

120

24.1

Every 3 months

175

35.2

Not known

76

15.3

What’s the target range of INR in AF patients with warfarin under 75 years old?

1.5–2.4

49

9.9

2.0–3.0

213

42.9

2.0–2.5

86

17.3

1.8–2.6

15

3

2.5–3.5

75

15.1

Not known

59

11.9

What’s the target range of INR in AF patients with warfarin over 75 years old

1.5–2.4

63

12.7

2.0–3.0

105

21.1

2.0–2.5

138

27.8

1.8–2.6

26

5.2

2.5–3.5

56

11.3

Not known

109

21.9

Which factor is susceptible to the anticoagulation effect of warfarin

The patient’s genes

213

42.9

Food

312

62.8

Drugs

420

84.5

Not known

49

9.9

What’s the antagonist that antagonizes warfarin’s anticoagulation

Vitamin K

455

91.5

Protamine

32

6.4

Prothrombin complex

93

18.7

Fresh plasma

135

27.2

Not known

16

3.2

Which of the following AF patients need to adjust warfarin dose

INR 2.0–3.0

32

6.4

INR 1.0–1.5

225

45.3

INR 3.8–4.5

291

58.6

INR 2.0–2.5 and age ≥ 75y

125

25.2

Not known

119

23.9

Which medication are the new oral anticoagulants (NOAC)?

Dabigatran

237

47.7

Rivaroxaban

341

68.6

Apixaban

316

63.6

Dicoumarin

85

17.1

Edoxaban

211

42.5

Not known

97

19.5

  1. INR: International normalized ratio; CHADS2-VASc: Congestive heart failure, hypertension, age ≥ 75 (doubled), diabetes, stroke (doubled), vascular disease score; HAS-BLED: Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/alcohol concomitantly; ECG: electrocardiogram; ORBIT: Outcomes Registry for Better Informed Treatment of Atrial Fibrillation