Table 2 Summary of the composition of pilocarpine HCl loaded ocular inserts
Formula | Polymer (type and concentration (%w/v)) | Plasticiser (glycerine) (mL) | Amount of pilocarpine HCl (mg) | Solvent volume (mL) |
|---|---|---|---|---|
T1 | 1% HPMC + 1.5% PVA | 1.0 | 1.0 | 50 |
T2 | 1% HPMC + 1% PVA | 1.0 | 1.0 | 50 |
T3 | 1% HPMC + 1% PVA | 1.0 | 2.0 | 50 |
T4 | 1% HPMC + 1.5% PVA | 1.0 | 2.0 | 50 |