Table 2 Selected MHC class I and class II epitopes with antigenicity, allergenicity, and toxicity
From: Multi-epitope-based vaccine designing against Junín virus glycoprotein: immunoinformatics approach
Sequence | Allele | Antigenicity | Allergenicity | Toxicity | |
|---|---|---|---|---|---|
Tc/MHC class I | |||||
FQTVSFSMV | HLA-A*02:06 | 1.51 | A | + | N |
KMKCFGNTA | HLA-A*30:01 | 1.22 | A | + | N |
TVSFSMVGL | HLA-A*68:02 | 1.83 | A | + | N |
ALNIALVAV | HLA-A*02:03 | 1.46 | A | + | N |
FVFLALAGR | HLA-A*68:01 | 1.52 | A | + | N |
NSYLNISDFR | HLA-A*68:01 | 0.88 | A | + | N |
TLNKSHLYIK | HLA-A*03:01 | 0.82 | A | + | N |
HTEFQTVSF | HLA-A*32:01 | 1.40 | A | + | N |
CPLPHRLNSL | HLA-B*07:02 | 1.21 | A | + | N |
Th/MHC class II | |||||
IGLHTEFQTVSFSMVGLF | HLA-DPA1*03:01/DPB1*04:02 | 1.24 | A | + | N |
NGKLCLMKAQPTSWPLQC | HLA-DPA1*02:01/DPB1*01:01 | 0.93 | A | + | N |
LDHVNTLHFLTRGKNIQL | HLA-DQA1*01:01/DQB1*05:01 | 1.12 | A | + | N |
GNASFQISFDDIAVLLPQ | HLA-DPA1*01:03/DPB1*02:01 | 0.93 | A | + | N |
NTLHFLTRGKNIQLPRRS | HLA-DRB1*15:01 | 0.89 | A | + | N |
FLQEALNIALVAVSLIAI | HLA-DRB1*01:01 | 0.88 | A | + | N |
SFSMVGLFSNNPHDLPLL | HLA-DRB1*07:01 | 0.96 | A | + | N |
QEALNIALVAVSLIAIIK | HLA-DRB1*13:02 | 0.90 | A | + | N |