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Table 2 The effect of Mupirocin: Ethyl cellulose ratio and stirring rate on production yield, EE, and mean particle size

From: Enhanced therapeutic approach for diabetic foot ulcers: comparative study and characterisation of mupirocin-loaded nanosponge gel with marketed formulation for accelerating wound healing and in vivo evaluation

Batches

Factors

Responses

Mupirocin: Ethyl cellulose

Stirring rate

Particle size (nm)

Entrapment efficiency (%)

Production yield (%)

F1

100:400

600

335.4 ± 4.25

76.93 ± 1.02

63 ± 2.14

F2

100:600

600

381.5 ± 2.13

85.73 ± 0.98

61 ± 1.26

F3

100:800

600

451.8 ± 3.36

88.72 ± 2. 55

69 ± 3.49

F4

100:400

1000

263.4 ± 1.71

79.10 ± 1.43

73 ± 2.51

F5

100:600

1000

189.5 ± 2.21

84.48 ± 3.70

65 ± 1.87

F6

100:800

1000

304.1 ± 3.32

89.84 ± 1.93

77 ± 3.64

F7

100:400

1400

148.5 ± 2.19

77.7 ± 3.02

61 ± 3.91

F8

100:600

1400

202.2 ± 1.02

82.14 ± 1.47

76 ± 1.22

F9

100:800

1400

212.6 ± 3.05

86.87 ± 2.52

74 ± 2.37

  1. αEach observation is the mean ± SD of three determinations