Future Journal of Pharmaceutical Sciences

Table 7 HET-CAM irritation score of the MP-NS Gel, NaOH (1%, positive control), and NaCl (0.9%, Negative control)

From: Enhanced therapeutic approach for diabetic foot ulcers: comparative study and characterisation of mupirocin-loaded nanosponge gel with marketed formulation for accelerating wound healing and in vivo evaluation

										Score
Samples			Non- irritant				Mild irritant			Moderate Irritant				Severe Irritant		Overall Score
Samples	Egg		Time (min)			Time	(min)			Time (min)				Time (min)
		0	0.5	2	5	0.5	2	5	0.5	2	5	0	0.5	2	5
MP-NS Gel	Egg 1	0	0	0	0.0	0	0	0	0	0	0	0	0	0	0
	Egg 2	0	0	0	0.0	0	0	0	0	0	0	0	0	0	0
	Egg 3	0	0	0	0.2	0	0	0	0	0	0	0	0	0	0
	Mean score	0	0	0	0.2	0	0	0	0	0	0	0	0	0	0	0
Positive Control (NaOH 1%)	Egg 1	0	0	0	0	0	0	0	0	0	0	0	14	17	19
	Egg 2	0	0	0	0	0	0	0	0	0	0	0	16	18	19
	Egg 3	0	0	0	0	0	0	0	0	0	0	0	16	18	20
	Mean score	0	0	0	0	0	0	0	0	0	0	0	14.5	16.1	18.7	16.43
Negative Control (NS 0.9%)	Egg 1	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	Egg 2	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	Egg 3	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	Mean score	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

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