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Table 8 Percent (%) drug released of marketed mupirocin ointment, mupirocin cream and prepared mupirocin-loaded nanosponge gel formulation

From: Enhanced therapeutic approach for diabetic foot ulcers: comparative study and characterisation of mupirocin-loaded nanosponge gel with marketed formulation for accelerating wound healing and in vivo evaluation

Time (hour)

Formulations (% Cumulative drug released)

Mupirocin ointment

Mupirocin cream

Mupirocin-loaded Nanosponge–Gel

0.5

39.81 ± 1.33

21.40 ± 1.31

8.17 ± 2.21

1

76.48 ± 2.41

39.50 ± 2.19

11.35 ± 1.21

2

84.47 ± 1.71

46.97 ± 2.85

15.30 ± 3.21

3

91.05 ± 3.57

55.95 ± 3.34

20.35 ± 2.21

4

95.51 ± 2.74

68.49 ± 1.79

27.69 ± 1.21

6

–

74.38 ± 2.11

42.15 ± 3.21

8

–

83.28 ± 1.42

47.15 ± 1.21

12

–

90.20 ± 3.64

58.60 ± 2.21

24

–

–

81.06 ± 2

  1. αEach observation is the mean ± SD of three determinations