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Fig. 4 | Future Journal of Pharmaceutical Sciences

Fig. 4

From: Cordycepin alleviates osteoarthritis by inhibiting chondrocyte ferroptosis via Keap1/Nrf2 axis

Fig. 4

Cordycepin inhibits ferroptosis of chondrocytes in vivo. a The experimental timeline for the animal study. b Immunohistochemical staining for Keap1 in mouse joint cartilage sections. bar = 200 μm. c Quantification of Keap1-positive cells. d Immunohistochemical staining for Nrf2 in mouse joint cartilage sections. bar = 200 μm. e Quantification of Nrf2-positive cells. f Immunofluorescence staining for Keap1 in joint cartilage. bar = 100 μm. g Quantification of Keap1-positive cells. h Immunohistochemical staining for Nrf2 in joint cartilage. bar = 100 μm. i Quantification of Nrf2-positive cells. *p < 0.05, **p < 0.01, n = 3

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