Table 2 Independent variables and their levels for optimization study
From: Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model
Factor | Name | Units | Minimum | Maximum | Coded Low | Coded High | Mean | SD |
|---|---|---|---|---|---|---|---|---|
A | HPMC K100 | % | 0.20 | 1.8 | − 1 ↔ 0.20 | + 1 ↔ 1.8 | 1.0000 | 0.6047 |
B | ERL 100 | % | 0.10 | 1.0 | − 1 ↔ 0.10 | + 1 ↔ 1.0 | 0.5500 | 0.3402 |
C | PEG 400 | % | 10.00 | 50.0 | − 1 ↔ 10.0 | + 1 ↔ 50.0 | 30.00 | 15.12 |