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Table 7 Model fit summary of in-vitro drug release

From: Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model

Source

Sequential p-value

Lack of Fit P-value

Adjusted R2

Predicted R2

 

Linear

0.0230

0.5932

0.4463

0.1929

Suggested

2FI

0.7942

0.4967

0.3257

− 0.5276

 

Quadratic

0.3386

0.5117

0.4191

− 1.2359

 

Cubic

0.5117

 

0.4483

 

Aliased