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Table 8 ANOVA table of in-vitro drug release

From: Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model

Source

Sum of Squares

df

Mean Square

F-value

p-value

 

Model

228.65

3

76.22

4.76

0.0230

Significant

A-HPMC K100

28.01

1

28.01

1.75

0.2127

 

B-ERL 100

10.22

1

10.22

0.6381

0.4413

 

C-PEG

190.42

1

190.42

11.89

0.0054

 

Residual

176.10

11

16.01

   

Lack of Fit

144.20

9

16.02

1.00

0.5932

Not significant

Pure Error

31.90

2

15.95

   

Cor Total

404.74

14