NCT number, current phase | Study design | Eligibility criteria | Arms of the study | Primary endpoints |
---|---|---|---|---|
NCT04493476, Phase II | A double-blind, prospective and placebo-regulated clinical trial to assess the response of combination therapy of Chinese herbal medicine and curcumin to lower the symptoms of endometriosis | Women having a confirmed diagnosis of endometriosis, women aged 18–45 years (reproductive age), no allergy to the ingredients of the intervention or the control | Intervention: Daily dietary dosing of Chinese medicine and curcumin given in the form of 800 mg capsules Control: Placebo (Invo capsules given in daily dosing) | The overall benefit in the symptoms of the disease |
NCT03016039 | A randomized, parallel assignment study of curcumin supplementation for endometriosis | Age above 18, patient with a diagnosis of pelvic inflammatory disease/Tubo ovarian abscess, surgical wound infection, endometritis | Intervention: Curcumin supplementation | Change in the Levels of C-reactive protein, change in the levels of white blood cells |
NCT03875261, Phase II | A randomized, single-group assignment study to examine the response of the effect of Cannabinoid (CBD) on pain experienced by endometriosis patients | Women falling in the age group of 18 and 40, having a confirmed diagnosis of endometriosis with clinical investigations, suffering from symptoms of pain, dysmenorrhea, etc. | Intervention: Participants administered cannabinoid derivates dosing between 1 and 12 puffs. Each puff contained 2–7 mg of delta-9-tetrahydrocannabinoland 2–5 mg of cannabidiol | Pressure threshold in hypogastrium that induces pain |
NCT02676713, Phase II | A randomized, prospective, multicentric study to evaluate the efficacy of Decoction (Chinese herbal medicine to treat infertility) in endometriosis | Women having a clinical diagnosis of endometriosis, endometriosis fertility index (EFI) score greater than 4 points, firstly undergoing laparoscopic surgery, the female of reproductive age (18–45 years) | Intervention: Decoction (Bupleurum 10 g, Cyperus 10 g, Salvia miltiorrhiza 20 g, Red peony 10 g, etc.) Placebo: Combination of maltodextrin, lactose, edible pigment, and taste masking agent | Pregnancy rate to an extent of six menstrual cycles |
NCT04150406, Current phase not given | A multicentric, randomized clinical trial to evaluate the potency of Flexofytol in endometriosis | Women of reproductive age (18–51 years), diagnosed with endometriosis, moderate to severe pelvic pain | Intervention: Flexofytol (Curcumin 42 mg 2 capsules administered for 4 months) Control: Placebo | Alteration in the baseline pain score |
NCT number not given | A randomized, multicentric clinical trial to evaluate the effect of Ashokarishta, Ashwagandha Churna, and Praval Pishti in patients suffering from menopausal syndrome | Females of age 40–55 years, suffering from amenorrhea for a period of greater than 12 months, were willing to comply with the study requirements, providing written consent to be included in the study | Intervention: Ashokarishta (25 mL daily), Ashwagandha (3 g twice daily with milk), Praval Pishti (250 mg twice daily) Control: Placebo | Improvement in the Menopausal rating scale (MRS), Incidences of adverse events (AEs) |