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Table 4 Liver function test parameters after 28 days of extract administration

From: Chemical characterization, safety profile and antileiomyoma effects of Tetrapleura tetraptera Taubert (Fabaceae) fruit ethanol extract in Sprague Dawley rats

 

Doses (mg/kg)

Parameters

Control

200

400

800

ALP (µ/L)

210.20 ± 32.91

251.20 ± 8.79

242.80 ± 28.9

249.80 ± 16.73

ALT (µ/L)

128.20 ± 12.29

112.60 ± 14.87

97.20 ± 15.19

118 ± 14.16

AST (µ/L)

195.20 ± 16.93

213.20 ± 28.52

143.6 ± 14.6

173.2 ± 17.48

Tb (mg/dL)

0.22 ± 0.02

0.22 ± 0.02

0.24 ± 0.02

0.2 ± 0.00

Cb (mg/dL)

0.10 ± 0.00

0.12 ± 0.02

0.1 ± 0.00

0.1 ± 0.00

Tp (g/dL)

6.28 ± 0.21

6.72 ± 0.22

6.22 ± 0.18

6.7 ± 0.27

ALB (g/dL)

3.26 ± 0.05

3.42 ± 0.17

3.20 ± 0.03

3.20 ± 0.06

GLo (g/dL)

3.02 ± 0.19

3.30 ± 0.17

3.02 ± 0.17

2.98 ± 0.22

  1. Data are expressed as mean ± SEM, n = 6. There was no significant difference between the groups according to Tukey–Kramer multiple comparison test P > 0.05, alkaline phosphatase (ALP), alanine aminotransferase (ALT) Aspartate aminotransferase (AST), total bilirubin (Tb), conjugated bilirubin (Cb), total protein (Tp), albumin (ALB), globulin (GLo)