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Table 5 Results of hematological assay after 28 days administration

From: Chemical characterization, safety profile and antileiomyoma effects of Tetrapleura tetraptera Taubert (Fabaceae) fruit ethanol extract in Sprague Dawley rats

Dose (mg/kg)

0

200

400

800

WBC (103/μL)

8.16 ± 0.58a

5.84 ± 0.52bc

5.84 ± 0.35bc

6.42 ± 0.54ac

LYM (%)

83.58 ± 1.94a

79.68 ± 3.85a

76.70 ± 2.12a

79.40 ± 2.04a

MID (%)

12.18 ± 1.25a

13.90 ± 2.26a

15.62 ± 1.52a

13.02 ± 1.35a

GRAN (%)

4.24 ± 0.75a

6.42 ± 1.60a

7.80 ± 0.90ba

7.60 ± 1.00a

RBC (106/μL)

5.67 ± 0.30a

5.94 ± 0.28a

5.90 ± 0.05a

6.21 ± 0.19a

HGB (g/dL)

11.06 ± 0.64a

11.74 ± 0.72a

11.60 ± 0.19a

12.20 ± 0.45a

HCT (%)

31.54 ± 1.82a

33.66 ± 1.82a

33.58 ± 0.74a

33.96 ± 1.30a

MCV (fL)

55.74 ± 1.90a

56.82 ± 2.06a

57.02 ± 1.40a

54.74 ± 1.22a

MCH (pg)

19.46 ± 0.29a

19.68 ± 0.61a

19.62 ± 0.22a

19.56 ± 0.24a

MCHC (g/dL)

35.08 ± 0.84a

34.80 ± 0.58a

34.56 ± 0.84a

35.88 ± 0.41a

RDW-SD (fL)

30.74 ± 2.76a

32.48 ± 2.07a

31.60 ± 2.08a

31.73 ± 1.77a

RDW-CV (%)

14.96 ± 0.94a

15.52 ± 0.57a

15.10 ± 0.74a

15.44 ± 0.56a

PLT (103/μL)

624.20 ± 76.12a

588.80 ± 19.99a

632.80 ± 70.34a

652.80 ± 39.78a

MPV (fL)

7.64 ± 0.07a

7.26 ± 0.23a

7.34 ± 0.20a

7.30 ± 0.08a

PDW (fL)

9.76 ± 0.41a

9.26 ± 0.61a

9.18 ± 0.33a

9.76 ± 0.12a

PCT (%)

0.47 ± 0.06a

0.43 ± 0.02a

0.47 ± 0.07a

0.47 ± 0.03a

P-LCR (%)

9.10 ± 1.43a

6.54 ± 1.76a

7.92 ± 1.44a

5.62 ± 0.77a

  1. Data are expressed as mean ± SEM, n = 6. Values in the test groups carrying the same letter as the control group are not significantly different according to Tukey–Kramer multiple comparison test (p > 0.05), white blood cell (WBC), lymphocytes (LYM), mid-range absolute count (MID), granulocytes (GRAN), red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width SD (RDW-SD), red blood cell distribution width CV (RDW-CV), platelet (PLT), mean platelet volume (MPV), platelet distribution width (PDW), platelets count (PCT), platelet larger cell ratio (P-LCR)