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Table 5 Changes in haematological parameters in phenylhydrazine-induced hyperbilirubinemic Wistar rats treated with solvent fractions of Vitellaria paradoxa root extracts

From: Solvent fractions of Vitellaria paradoxa root extract suppress phenylhydrazine-mediated jaundice in Wistar rats

GROUP

WBC 103/uL

HGB g/dL

RBC 106/uL

HCT (%)

PLT 103/uL

Control

5.09 ± 1.58cb

16.62 ± 0.98bc

8.15 ± 0.11bc

47.28 ± 0.33 bc

349.4 ± 12.1bc

PHZ only

15.69 ± 1.57*

7.09 ± 0.49*

4.05 ± 0.33*

29.8 ± 0.50*

107.6 ± 9.21*

PHZ + n-hexane

4.92 ± 1.81*bc

14.51 ± 0.23bc

7.62 ± 3.15bc

45.26 ± 0.18 bc

329.0 ± 10.3bc

PHZ + n-butanol

13.09 ± 0.43*c

7.86 ± 0.12*c

4.10 ± 2.22*c

32.24 ± 0.21*c

109.2 ± 11.7*c

PHZ + ethylacetate

4.51 ± 0.52*c

15.98 ± 0.32*c

7.36 ± 1.46*c

44.98 ± 0.16 bc

339.2 ± 12.23bc

PHZ + aqueous

14.12 ± 0.65*

9.05 ± 0.3*

4.53 ± 2.14*

30.05 ± 0.43*

109.3 ± 13.21*

  1. 50 mg/kg of phenylhydrazine intraperitoneal (PHZ): n-hexane, n-butanol, ethylacetate and aqueous represents the different fractions of the extracts: BWC: body weight change: values are presented as mean ± SD (n = 7):*values differ significantly from control (p < 0.05): bvalues are not significantly different from each other (p < 0.05): cvalues differ significantly as compared with PHZ only (p < 0.05)