Table 6 Changes in liver function parameters in phenylhydrazine-induced hyperbilirubinemic Wistar rats treated with solvent fraction of Vitellaria paradoxa root extracts

Control

0.91 ± 0.02 ^bc

0.31 ± 0.01^bc

19.12 ± 0.13 ^bc

69.21 ± 0.20 ^bc

36.23 ± 0.55 ^bc

3.61 ± 0.32 ^bc

7.93 ± 0.05 ^bc

PHZ only

2.30 ± 0.11*

0.90 ± 0.21*

36.18 ± 0.24*

152.10 ± 0.48*

61.02 ± 0.14*

1.85 ± 0.01*

3.43 ± 0.16*

PHZ + n-hexane

0.93 ± 0.31^bc

0.34 ± 0.13 ^bc

19.15 ± 0.11 ^bc

68.92 ± 0.32 ^bc

38.80 ± 0.13^bc

3.32 ± 0.15^bc

7.91 ± 0.02^bc

PHZ + n-butanol

2.15 ± 0.22*^c

0.85 ± 0.21*^c

32.04 ± 0.21*^c

149.00 ± 0.20*^c

57.00 ± 0.55*^c

1.95 ± 0.21*^c

3.25 ± 0.05*^c

PHZ + Ethylacetate

2.19 ± 0.12^bc

0.88 ± 0.22^bc

33.18 ± 0.19*^c

147.21 ± 0.65*^c

59.05 ± 0.54*^c

1.91 ± 0.05*^c

3.40 ± 0.13^,bc

PHZ + Aqueous

2.27 ± 0.03*

0.87 ± 0.11*

31.16 ± 0.19*

148 ± 0.47*

59.80 ± 0.18*

1.94 ± 0.19*

3.16 ± 0.08*