Table 9 Characterization results of NDFX-loaded transethosomal gel
Evaluation parameters | TEG 1 (Carbopol 1%) | TEG 2 (Carbopol 2%) | TEG 3 (HPMC K4M 2%) | TEG 4 (HPMC K4M 3%) |
|---|---|---|---|---|
Color | White Opaque | White Opaque | Off-White | Off-White |
pH | 7.12 ± 0.5 | 6.95 ± 0.05 | 6.31 ± 0.0.12 | 6.42 ± 0.23 |
Viscosity (cP) | 971 ± 15 | 1112 ± 12 | 794 ± 14 | 820 ± 10 |
Spreadability (g cm2/s) | 9.2 ± 0.25 | 8.83 ± 0.45 | 12.56 ± 0.62 | 10.35 ± 0.82 |
Drug content (%) | 92 ± 1.2 | 87 ± 1.8 | 86 ± 0.8 | 84 ± 0.5 |