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Future Journal of Pharmaceutical Sciences
Fig. 19 | Future Journal of Pharmaceutical Sciences

Fig. 19

From: Design, synthesis, 2D-QSAR, molecular dynamic simulation, and biological evaluation of topiramate–phenolic acid conjugates as PPARγ inhibitors

Fig. 19

Effect of T3 on 3T3-L1 preadipocytes PPARγ expression (i) comparative downregulation of PPARϒ expressions of T3 with respect to positive control GW9662 and normal control (untreated 3T3-L1 cells) (ii) PPARϒ expressions of T3, positive control GW9662 and normal control (untreated 3T3-L1 cells) relative to β-actin. The values are expressed as mean ± standard deviation for n = 3 biological repeats (*p < 0.05 and **p < 0.01)

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