Future Journal of Pharmaceutical Sciences

Table 4 Training set statistical parameters for best three models

From: Design, synthesis, 2D-QSAR, molecular dynamic simulation, and biological evaluation of topiramate–phenolic acid conjugates as PPARγ inhibitors

Fitting criteria	Model1	Model 11	Model 21
R²	0.9912	0.9895	0.9879
R²adj	0.9909	0.9893	0.9878
R²–R²adj	0.0003	0.0002	0.0001
LOF	0.0001	0.0001	0.0001
Kxx	0.2541	0.3521	0.0000
Delta K	0.2064	0.2570	0.9940
RMSE tr	0.0074	0.0080	0.0086
MAE tr	0.0056	0.0061	0.0066
RSS tr	0.0047	0.0056	0.0065
CCC tr	0.9956	0.9947	0.9939
S	0.0076	0.0082	0.0087
F	3108.9384	3966.4605	6968.4382

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