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Table 5 Predicted pIC50 values of designed conjugates

From: Design, synthesis, 2D-QSAR, molecular dynamic simulation, and biological evaluation of topiramate–phenolic acid conjugates as PPARγ inhibitors

Compound code

R

Predicted pIC50

T1

7.005003569

T2

7.038592667

T3

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7.08435656

T4

6.991701765

T5

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7.019504227

T6

7.003357836

T7

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7.066946934

T8

7.030767462

T9

7.019279445

T10

6.988112667