Fig. 4

Representative photomicrographs of anti-insulin immunohistochemistry-stained rat pancreatic Sects. (400x). A Control group shows a strong homogeneous distribution of insulin immunostaining in β cells. B & C Groups STZ-30 and STZ-30-Cap illustrate moderate heterogeneous insulin immunostaining in β cells. D STZ-40 group exhibits moderate insulin immunostaining in β cells. E Group STZ-40-Cap demonstrates weak insulin immunostaining of β cells. F & G STZ-50 and STZ-50-Cap exhibit faint heterogeneous insulin immunostaining in β cells. H Histogram representing mean area % anti-insulin immunostained sections; * denotes significant difference compared to control, # denotes significant difference compared to STZ-30, $ denotes significant difference compared to STZ-30-Cap, € denotes significant difference compared to STZ-40, ¥ denotes significant difference compared to STZ-40-Cap, and @ denotes significant difference compared to STZ-50. STZ Streptozotocin, Cap Captopril