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Fig. 5 | Future Journal of Pharmaceutical Sciences

Fig. 5

From: Captopril pretreatment augments diabetogenic response to streptozotocin administration: experimental in vivo rat model

Fig. 5

Representative photomicrographs of anti-TNF-α immunohistochemistry-stained rat pancreatic Sects. (400x). A The control group shows negative immunostaining of β cells with TNF-α. B & C The groups STZ-30 and STZ-30-Cap exhibit moderate TNF-α immunostaining in β cells. D Group STZ-40 exhibits moderate TNF-α immunostaining. E Group STZ-40-Cap demonstrates strong TNF-α immunostaining of β cells. F STZ-50 illustrates strong TNF-α immunostaining of β cells. G STZ-50-Cap exhibits intensive immunostaining of β cells with TNF-α. H Histogram illustrating optical density of anti-TNF-α immunostained sections. * denotes significant difference compared to control, # denotes significant difference compared to STZ-30, $ denotes significant difference compared to STZ-30-Cap, € denotes significant difference compared to STZ-40, ¥ denotes significant difference compared to STZ-40-Cap, and @ denotes significant difference compared to STZ-50. TNF-α Tumor necrosis alpha, STZ Streptozotocin, Cap Captopril

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