Table 2 Cytotoxic effects of formulations NIO 14 to NIO 17 on murine tumor cell line B16F10 cells
From: Size-dependent effects of niosomes on the penetration of methotrexate in skin layers
Treatment | % Growth inhibition at concentration (μg/mL) | GI50 (μg/mL) | |||
|---|---|---|---|---|---|
10 | 20 | 40 | 80 | ||
NIO 14 | 9.1 | 9.9 | 6.7 | 6.9 | 2.5311 |
NIO 15 | 4.3 | − 0.5 | − 2.1 | 7.5 | 8.05738 |
NIO 16 | 1.7 | − 0.8 | 6.7 | 14.1 | 40.2238 |
NIO 17 | 5.9 | 5.8 | 14.8 | 32.3 | 38.7176 |
ADR | − 70.5 | − 72.1 | − 73.4 | − 56.4 | 2.16266 |