Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

Future Journal of Pharmaceutical Sciences

Table 11 Short-term stability results of amivantamab

Replicate no	HQC (75.0 ng/ml)	LQC (25.0 ng/ml)	MQC (50.0 ng/ml)
Replicate no	Concentration (ng/ml)
1	74.8	23.2	49.3
2	74.8	23.2	49.3
3	74.2	22.6	48.7
4	74.2	23.2	49.3
5	74.8	22.6	48.7
6	75.4	23.2	48.7
Mean	74.7	23.0	49.0
SD	0.5	0.3	0.3
% CV	0.6	1.4	0.7
% Mean accuracy	99.6%	92.1%	98.0%