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Table 19 Wet extract stability results of amivantamab at 12 h

From: Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

Replicate no

HQC (75.0 ng/ml)

LQC (25.0 ng/ml)

MQC (50.0 ng/ml)

Concentration (ng/ml)

1

75.4

25.1

49.9

2

73.6

25.1

49.3

3

76.0

25.1

49.3

4

76.7

24.5

49.3

5

74.8

23.9

50.6

6

76.7

24.5

49.9

Mean

75.5

24.7

49.7

SD

1.2

0.5

0.5

% CV

1.6

2.1

1.0

% Mean accuracy

100.7%

98.8%

99.5%