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Table 21 Dry extract stability results of amivantamab at 12 h

From: Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

Replicate no

HQC (75.0 ng/ml)

LQC (25.0 ng/ml)

MQC (50.0 ng/ml)

Concentration (ng/ml)

1

75.4

25.7

49.9

2

75.4

25.1

49.3

3

76.0

25.1

49.3

4

74.2

24.5

49.9

5

76.7

24.5

49.9

6

74.8

23.8

49.9

Mean

75.4

24.8

49.7

SD

0.9

0.7

0.3

% CV

1.2

2.6

0.6

% Mean accuracy

100.6%

99.2%

99.5%