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Table 6 Specificity results of amivantamab

From: Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

S. no

Sample ID

Intensity (cps)

% Interference

Pass/fail

Amivantamab

Trastuzumab

Amivantamab

Trastuzumab

1

Std Blank 1

0

0

0

0

Pass

2

LLOQ 1 (5 ng/ml)

0.369 × 105

4.237 × 105

0

0

Pass

3

Std Blank 2

0

0

0

0

Pass

4

LLOQ 2 (5 ng/ml)

0.361 × 105

4.221 × 105

0

0

Pass

5

Std Blank 3

0

0

0

0

Pass

6

LLOQ 3 (5 ng/ml)

0.365 × 105

4.234 × 105

0

0

Pass

7

Std Blank 4

0

0

0

0

Pass

8

LLOQ 4 (5 ng/ml)

0.367 × 105

4.225 × 105

0

0

Pass

9

Std Blank 5

0

0

0

0

Pass

10

LLOQ 5 (5 ng/ml)

0.363 × 105

4.211 × 105

0

0

Pass

11

Std Blank 6

0

0

0

0

Pass

12

LLOQ 6 (5 ng/ml)

0.364 × 105

4.240 × 105

0

0

Pass