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Table 8 Precision and accuracy results of amivantamab

From: Bioanalytical method development and validation for quantification of amivantamab in rat plasma by LC-MS/MS

Replicate no

HQC (75.0 ng/ml)

MQC (50.0 ng/ml)

LQC (25.0 ng/ml)

LLQC (5.0 ng/ml)

Concentration (ng/ml)

1

74.8

49.9

24.5

4.6

2

74.8

49.9

25.1

4.6

3

75.4

48.7

25.1

4.6

4

75.4

49.3

25.1

5.2

5

73.6

49.9

25.1

4.6

6

74.2

49.9

25.1

4.6

Mean

74.7

49.6

24.9

4.7

SD

0.7

0.5

0.3

0.3

% CV

0.9

1.0

1.0

5.3

% Mean accuracy

99.6%

99.3%

99.9%

94.2%