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Table 4 Effect of Paederia foetida whole plant extract (200, 400 mg/kg/day, p.o., for 4 weeks) on serum potassium value, in Amphetamine-induced hypertensive rats and taking Hydralazine as a standard

From: Unveiling geniposide from Paederia foetida as a potential antihypertensive treatment: an integrated approach involving in vivo and computational methods

Serum K+(mMol/ml)

Treatment groups (mg/kg)

1st week

2nd week

3rd week

4th week

Normal control

5.15 ± 0.17**

5.29 ± 0.09**

5.31 ± 0.09**

5.26 ± 0.13**

Amphetamine (5)

5.29 ± 0.16**

5.38 ± 0.07**

5.49 ± 0.10**

5.36 ± 0.10**

Amphetamine (5) + Paederia foetida(P.F.)(200)

5.26 ± 0.11**

5.33 ± 0.13**

5.39 ± 0.03**

5.36 ± 0.10**

Amphetamine (5) + Paederia foetida(P.F.)(400)

5.23 ± 0.17**

5.42 ± 0.14**

5.36 ± 0.15**

5.32 ± 0.09**

Amphetamine (5) + Hydralazine(25)

5.20 ± 0.03**

5.27 ± 0.04**

5.23 ± 0.06**

5.24 ± 0.00**

  1. Values are expressed as mean ± std, n = 6. Differences were considered significant at *P value of < 0.05. For numerical results, analysis of variance (ANOVA) was performed using GraphPad InStat version 3
  2. **indicates level of significance of ANOVA result