Table 2 Effect of solvent extraction methods on the biological activity of artichoke extract
From: Artichoke extracts in cancer therapy: do the extraction conditions affect the anticancer activity?
Solvent | Anticancer activity |
|---|---|
Ethanol | *Leukaemia (L-120 and HL-60): 60–90% anti-proliferation *Liver (HepG2): 50–80% (cellular death) *Mesothelioma (MSTO-211H and MPP-89): migration inhibition by 50 and 35%, respectively |
Methanol | *Liver (HepG2): 50–80% (cellular death) *Breast (MCF-7, T47D and BT549): 60–80% (cellular death) *Prostate and melanoma: about 50% (cellular death) *Ovary, lung, brain, bone and leukaemia: > 50% (cellular death) |
Hexane | *Colon (DLD1): 20–100% (cellular death) |