Fig. 1From: Recent advances of non-ionic surfactant-based nano-vesicles (niosomes and proniosomes): a brief review of these in enhancing transdermal delivery of drugPossible mechanisms of action of niosomes and proniosomes for skin penetration in topical and transdermal drug delivery. a Release of drug molecules by niosomes. b Niosomes adsorption and fusion with stratum corneum. c Penetration of niosomes through intact sc. d Components of niosomes act as penetration enhancer and increase absorption of drug. e Penetration of niosomes through hair follicles or pilosebaceous units [16]Back to article page