Liposomes | Niosomes/ proniosomes | Reference |
---|---|---|
1. More expensive | 1. Less expensive | [123] |
2. Require special methods of storage and handling purpose | 2. Does not require any special conditions | [123] |
3. Phospholipids may be neutral or charged, makes the preparation unstable | 3. Non-ionic surfactants are uncharged, makes the preparation more stable | [107] |
4. Less shelf-life | 4. Long shelf-life | [107] |
5. Physical and chemical instability | 5. Highly stable | [107] |