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Table 6 Genes whose variants decrease the risk of DM and CVD

From: Diabetes and cardiovascular disease: inter-relation of risk factors and treatment

Gene

Protein function

PCSK9

Proprotein convertase subtilisin/Kexin type 9. Metabolism of plasma cholesterol [108]

CELSR2-PSRC1-SORT1

CELSR2 belongs to the cadherin superfamily; carry out contact mediated-communication [108]