Antilithiatic effect of C. dactylon, E. officinalis, K. pinnata, and B. nutans ethyl acetate fraction on glyoxylate-induced nephrolithiasis

Future Journal of Pharmaceutical Sciences

Table 2 Effect of ethyl acetate fraction of C. dactylon, E. officinalis, K. pinnata, and B. nutans on different urine parameter ratios of glyoxalate induced nephrolithiatic mice

Dose (mg/kg)	Ethyl acetate fraction of *C. dactylon*				Ethyl acetate fraction of *E. officinalis*				Ethyl acetate fraction of *K. pinnata*				Ethyl acetate fraction of *B. nutans*
Dose (mg/kg)	Ca/Ox	Ca/Cr	PO₄/Cr	Mg/Cr	Ca/Ox	Ca/Cr	PO₄/Cr	Mg/Cr	Ca/Ox	Ca/Cr	PO₄/Cr	Mg/Cr	Ca/Ox	Ca/Cr	PO₄/Cr	Mg/Cr
Vehicle control	1.13	0.14	0.33	0.31	1.13	0.14	0.33	0.31	1.13	0.14	0.33	0.31	1.13	0.14	0.33	0.31
Negative control	0.07	0.38	1.39	0.14	0.07	0.38	1.39	0.14	0.07	0.38	1.39	0.14	0.07	0.38	1.39	0.14
Cystone (750)	1.03	0.09	0.28	0.21	1.03	0.09	0.28	0.21	1.03	0.09	0.28	0.21	1.03	0.09	0.28	0.21
Low dose	0.80	0.24	0.91	0.10	0.68	0.29	0.91	0.26	0.72	0.26	0.75	0.19	0.76	0.26	0.78	0.19
Median dose	1.00	0.22	0.75	0.13	0.80	0.20	0.74	0.23	0.76	0.19	0.48	0.18	0.77	0.20	0.56	0.18
High dose	0.95	0.18	0.46	0.14	0.77	0.16	0.48	0.24	0.75	0.11	0.36	0.20	0.85	0.14	0.38	0.17

All the ratios were calculated converting the individual values in mg/dl unit
Ca/Ox calcium/oxalate, Ca/Cr calcium/creatinine, PO₄/Cr phosphate/creatinine, and Mg/Cr magnesium/creatinine ratio