Preparation, characterization and evaluation of fenofibrate: benzoic acid cocrystals with enhanced pharmaceutical properties

Future Journal of Pharmaceutical Sciences

Table 3 Serum lipidaemic data

Groups	Dose	TC	TG	HDL	LDL	VLDL
I	Control (Triton X100-300 mg/kg)	173.05 ± 3.89	169.48 ± 4.46	29.47 ± 4.53	109.33 ± 2.89	28.86 ± 3.49
II	Cocrystals (25 mg/kg)	159.67 ± 4.85	122.31 ± 3.82	27.80 ± 0.59	102.10 ± 2.31	26.73 ± 1.41
III	Cocrystals (50 mg/kg)	89.23 ± 3.72	81.37 ± 3.35	38.12 ± 1.13	45.97 ± 2.09	15.83 ± 0.98
IV	FB (50 mg/kg)	108.2 ± 2.55	98.55 ± 2.03	33.21 ± 1.98	58.31 ± 3.61	20.76 ± 2.39

Values are mean of 6 ± S.D, TC—total cholesterol, TG—triglycerides, HDL—high-density lipids, LDL—low-density lipids, VLDL—very-low-density lipids