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Table 2 Master formulation of triamcinolone acetonide eye drops suspension

From: Formulation, optimization, qualitative and quantitative analysis of new dosage form of corticosteroid

Sr. # Excipient Qty/ mL Grade Role/function
1 Triamcinolone acetonide 2.00 mg BP/USP Active ingredient
2 Polysorbate (Tween 80) 30.0 mg USP/NF Solvent, antioxidant
3 PEG-12 glyceryl dimeristate 70.0 mg USP/NF Solubilizer, emulsifier
4 Ethyl alcohol 10 µL USP/NF Solvent, antibacterial
5 Citric acid anhydrous 1.0 mg USP/NF Antioxidant, preservative
6 Sodium citrate dihydrate 4.0 mg USP/NF Anticoagulant, buffers
7 Benzalkonium chloride 0.15 mg USP/NF Preservative, antimicrobial agent & surfactant
8 Water for injection (q.s) 1.0 mL USP/BP Solvent