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Future Journal of Pharmaceutical Sciences
Fig. 14 | Future Journal of Pharmaceutical Sciences

Fig. 14

From: Elucidation of possible mechanisms of the antidiabetic potential of Zn-loaded Bryophyllum pinnatum (Lam.) extracts in experimental animal models

Fig. 14

Sources of dietary flavonoids. These flavonoids possess antidiabetic and antioxidant effects by various mechanisms such as inhibition of serum IL-1β and IL-6/1β, enhancing the β-islets cells, inhibition of gluconeogenesis and glucose release in blood from liver, stimulation of glycogenesis, inhibition of HMG-CoA reductase and SREBP-1, reduction in the level of triglycerides, stimulation of glucose sensitivity by stimulation of phosphorylation IRS and PI3K-PKB/Akt pathways, etc.

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