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Table 21 Stability studies of n-acetyl l-cysteine

From: Development and validation of a stability indicating green analytical method for the simultaneous estimation of l-glutathione, n-acetyl l-cysteine and Vitamin C in marketed formulation using UV–visible spectroscopy

Stress conditions

Time (h)

% Degradation

Acidic hydrolysis (0.1N HCl)

24

30.14

Alkaline hydrolysis (0.1N NaOH)

24

19.03

Oxidative degradation (30% H2O2)

24

68.72

Photolytic degradation

9

10.34

Thermal degradation

6

15.19