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Future Journal of Pharmaceutical Sciences
Fig. 5 | Future Journal of Pharmaceutical Sciences

Fig. 5

From: Development of superior chitosan–EDTA microparticles as an adsorbent base for solidifying the self-emulsifying drug delivery systems

Fig. 5

Contour plots of practical yield (Y), zeta potential (ZP) and particle size (PS): A SE-CHEM, B SD-CHEM. A In this contour plot, white area shows the design space where the Y and ZP will be maximum and PS will be minimum. So, the desirability for percentage yield (%) and zeta potential (mV) is always more than 84%, 8 mV and for particle size (µm) < 6 µm can be obtained with CH/EDTA ratio (60:40) and drying temperature (70 °C). B The white area of contour plot, shows the design space where the Y and ZP will be maximum and PS will be minimum. So, from these optimization studies, the desirability for percentage yield (%) and zeta potential (mV) are always more than 55%, 4 mV and for particle size (µm) < 3 µm can be obtained with CH/EDTA ratio (50:50) and drying temperature (110 °C)

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