Walter TH, Andrews RW (2014) Recent innovations in UHPLC columns and instrumentation. Trends Anal Chem 63:14–20. https://doi.org/10.1016/j.trac.2014.07.016
Article
CAS
Google Scholar
Singh S, Prasad L, Kumar V, Roy S, Patnaik SK (2016) Ultra performance liquid chromatography: high throughput analysis over high performance liquid chromatography. Int J Eng Allied Sci 2:19–25
Google Scholar
Samatha Y, Srividya A, Ajitha A, Rao VUM (2015) Ultra performance liquid chromatography (UPLC). World J Pharm Pharm Sci 8:356–367
Google Scholar
Swartz ME (2005) UPLC: an introduction and review. J Liq Chromatogr Relat Technol 28:1253–1263. https://doi.org/10.1081/JLC-200053046
Article
CAS
Google Scholar
Ht Quantitative Analysis for a drug mixture by LC/MS/MS: UPLC-MS/MS and HPLC-MS/MS Compared (2005) water. http://www.water.com.
Novakova L, Matysova L, Solich P (2006) Advantages of application of UPLC in pharmaceutical analysis. Talanta 68:908–918. https://doi.org/10.1016/j.talanta.2005.06.035
Article
CAS
PubMed
Google Scholar
Chawla G, Ranjan C (2016) Principle, instrumentation, and applications of UPLC: A novel technique of liquid chromatography. Open Chem J 3:1–16. https://doi.org/10.2174/1874842201603010001
Article
Google Scholar
Phalke P, Kavade S (2013) Review on hyphenated techniques. Int J Chem Stud1:157–165
UPLC columns and consumables. https://www.waters.com//UPLCColumns 2014.
Acquity UPLC column by water. https://www.waters.com/waters/acquitycolumns 2015.
Acquity UPLC column solution. https://www.waters.com//UPLCColumns 2009.
Acquity UPLC columns by waters. https://www.waters.com 2008.
Roge AB, Firke SN, Dhane RM, Gunjkar VJ, Vadvalkar SM (2011) Novel achievement of HPLC: UPLC. Int JPharm Tech Res 3:1423–1429
CAS
Google Scholar
Narwate BM, Ghule PJ, Ghule AV, Darandale AS, Wagh JG (2014) Ultra performance liquid chromatography: A new resolution in chromatography. Int J Pharm Drug Anal 2:25–34
Google Scholar
Principles and applications of LC-MS/ (2012) MS for the quantitative bioanalysis of analytes in various biological samples. In: tandem mass spectrometry-applications and principles. http://www.intechopen.com
Google Scholar
Khatri N, Gupta A, Taneja R, Bilandi A, Beniwal P (2012) A review on mass spectrophotometry detectors. Int Res J Pharm 3:33–42
CAS
Google Scholar
De Hoffmann E (2000) Mass spectrometry. Kirk-Othmer Encyclopedia of Chemical Technology.
Mass Spectrometry Detectors. https://www.colorado.edu/mass spectrophotmetry detector/. 2009 .
Mass Spectrometry detectors. http://www.chm.bris.ac.uk/ms/detectors. Accessed 28 Nov 2018.
Higashi T, Shimada K, Toyooka T (2010) Advances in determination of vitamin D related compounds in biological samples using liquid chromatography–mass spectrometry: a review. JChromatogr B 878:1654–1661. https://doi.org/10.1016/j.jchromb.2009.11.026
Article
CAS
Google Scholar
Roux A, Lison D, Junot C, Heilier JF (2011) Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology. Clin Biochem 44:119–135. https://doi.org/10.1016/j.clinbiochem.2010.08.016
Article
CAS
PubMed
Google Scholar
Zoerner AA, Gutzki FM, Batkai S, May M, Rakers C, Engeli S, Jordan J, Tsikas D (2011) Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: a comprehensive review from an analytical and biological perspective. Biochim Biophys Acta 1811:706–723. https://doi.org/10.1016/j.bbalip.2011.08.004
Article
CAS
PubMed
Google Scholar
Gosetti F, Mazzucco E, Gennaro MC, Marengo E (2013) Ultra high performance liquid chromatography tandem mass spectrometry determination and profiling of prohibited steroids in human biological matrices. A review. J Chromatogr B 927:22–36. https://doi.org/10.1016/j.jchromb.2012.12.003
Article
CAS
Google Scholar
Bantscheff M, Lemeer S, Savitski MM, Kuster B (2012) Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present. Anal Bioanal Chem 404:939–965. https://doi.org/10.1007/s00216-012-6203-4
Article
CAS
PubMed
Google Scholar
Viant MR, Sommer U (2013) Mass spectrometry based environmental metabolomics: a primer and review. Metabolomics 9:144–158. https://doi.org/10.1007/s11306-012-0412-x
Article
CAS
Google Scholar
Motilva MJ, Serra A, Macia A (2013) Analysis of food polyphenols by ultra high-performance liquid chromatography coupled to mass spectrometry: an overview. J Chromatogr A 1292:66–82. https://doi.org/10.1016/j.chroma.2013.01.012
Article
CAS
PubMed
Google Scholar
Pratima NA, Shraddha B, Zibran S (2013) Review of ultra performance liquid chromatography and its applications. Int J Res Pharm Sci 3:1–42
Google Scholar
Gouveia MJ, Brindley PJ, Santos LL, da Costa JMC, Gomes P, Vale N (2013) Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: a review. Metabolism 62:1206–1217. https://doi.org/10.1016/j.metabol.2013.04.003
Article
CAS
PubMed
PubMed Central
Google Scholar
Kailemia MJ, Ruhaak LR, Lebrilla CB, Amster IJ (2013) Oligosaccharide analysis by mass spectrometry: a review of recent developments. Anal Chem 86:196–212. https://doi.org/10.1021/ac403969n
Article
CAS
PubMed
PubMed Central
Google Scholar
Kortz L, Dorow J, Ceglarek U (2014) Liquid chromatography–tandem mass spectrometry for the analysis of eicosanoids and related lipids in human biological matrices: a review. J Chromatogr B 964:1–11. https://doi.org/10.1016/j.jchromb.2014.01.046
Article
CAS
Google Scholar
Desai TK, Mahajan AA, Thaker A (2012) Ultra performance liquid chromatography: a step ahead to HPLC. Int J Pharm Res Rev 2:61–68
Google Scholar
Kole PL, Venkatesh G, Kotecha J, Sheshala R (2011) Recent advances in sample preparation techniques for effective bioanalytical methods. Biomed Chromatogr 25(1–2):199–217. https://doi.org/10.1002/bmc.1560
Carlier M, Stove V, Roberts JA, Van de VE, De WJJ, Verstraete AG (2012) Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method. Int J Antimicrob Agents 40:416–422. https://doi.org/10.1016/j.ijantimicag.2012.06.022
Article
CAS
PubMed
Google Scholar
Zhao L, Zhao Y, Li Q, Chen X, Xiao F, He B, Wang J, Bi K (2012) A fast, sensitive, and high throughput method for the determination of cefuroxime lysine in dog plasma by UPLC–MS/MS. Talanta 89:84–90. https://doi.org/10.1016/j.ijantimicag.2012.06.022
Article
CAS
PubMed
Google Scholar
Wang YJ, Wu YT, Lin JY, Chu CH, Huang HY, Wang YC, Chen JK, Yang CS (2012) Rapid quantitative analysis of clarithromycin in rat plasma by UPLC–MS/MS after intravenous injection of the clarithromycin-loaded ultrafine PLGA nanoparticles. J Chromatogr B 895:178–181. https://doi.org/10.1016/j.jchromb.2012.03.022
Article
CAS
Google Scholar
Oufir M, Sampath C, Butterweck V, Hamburger M (2012) Development and full validation of an UPLC-MS/MS method for the determination of an anti-allergic indolinone derivative in rat plasma, and application to a preliminary pharmacokinetic study. J Chromatogr B 902:27–34. https://doi.org/10.1016/j.jchromb.2012.06.009
Article
CAS
Google Scholar
Marca GL, Giocaliere E, Villanelli F, Malvagia S, Funghini S, Ombrone D, Filippi L, Gaudio MD, Martino MD, Galli L (2012) Development of an UPLC–MS/MS method for the determination of antibioticertapenem on dried blood spots. J Pharm Biomed Anal 61:108–113. https://doi.org/10.1016/j.jpba.2011.12.018
Article
CAS
PubMed
Google Scholar
Chahbouni A, Dungen FAVD, Vos RM, den Burger JC, Sinjewel A, Wilhelm AJ, Veldkamp AI, Swart EL, van Weissenbruch MM (2015) An UPLC–MS detection method for the quantification of five antibiotics in human plasma. Bioanalysis 7:2321–2329. https://doi.org/10.4155/bio.15.121
Article
CAS
PubMed
Google Scholar
Wang XS, Sun JC, Yang RN, Ren J, Liang S, Sun M, Wang YF, Gao SG (2014) Determination of cephalomannine in rat plasma by gradient elution UPLC–MS/MS method. J Chromatogr B 963:70–74. https://doi.org/10.1016/j.jchromb.2014.05.045
Article
CAS
Google Scholar
Yu HC, Pan CW, Xie QP, Zheng Y, Hu YZ, Lin YM (2016) Simultaneous determination of tedizolid and linezolid in rat plasma by ultra performance liquid chromatography tandem mass spectrometry and its application to a pharmacokinetic study. J Chromatogr B 1011:94–98. https://doi.org/10.1016/j.jchromb.2015.12.056
Article
CAS
Google Scholar
Li Y, Sun Y, Du F, Yuan K, Li C (2008) Pulse gradient, large-volume injection, high-throughput ultra-performance liquid chromatographic/tandem mass spectrometry bioanalysis for measurement of plasma amrubicin and its metabolite amrubicinol. J Chromatogr A 1193:109–116. https://doi.org/10.1016/j.chroma.2008.04.014
Article
CAS
PubMed
Google Scholar
Chen Y, Zhang S, Chen D, Zhou M, Zheng J, Xiang Z (2015) An UPLC-MS/MS method for determination of solasonine in rat plasma and its application of a pharmacokinetic and bioavailability study. J Chromatogr B 985:1–5. https://doi.org/10.1016/j.jchromb.2015.01.017
Article
CAS
Google Scholar
Wang X, Wang S, Ma J, Ye T, Lu M, Fan M, Deng M, Hu L, Gao Z (2015) Pharmacokinetics in rats and tissue distribution in mouse of berberrubine by UPLC-MS/MS. J Pharm Biomed Anal 115:368–374. https://doi.org/10.1016/j.jpba.2015.07.031
Article
CAS
PubMed
Google Scholar
Iqbal M, Ezzeldin E, Al-Rashood KA, Shakeel F (2015) A validated UPLC–MS/MS assay using negative ionization mode for high-throughput determination of pomalidomide in rat plasma. J Chromatogr B 983:76–82. https://doi.org/10.1016/j.jchromb.2014.12.036
Article
CAS
Google Scholar
Du P, Li N, Wang H, Yang S, Song Y, Han X, Shi Y (2013) Development and validation of a rapid and sensitive UPLC–MS/MS method for determination of total docetaxel from a lipid microsphere formulation in human plasma. J Chromatogr B 926:101–107. https://doi.org/10.1016/j.jchromb.2013.02.006
Article
CAS
Google Scholar
Iqbal M, Wani TA, Khalil NY, Darwish IA (2013) Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma. Chem Cent J 7:1–9. https://doi.org/10.1186/1752-153X-7-7
Article
CAS
Google Scholar
Zhang SQ, Chen GH (2008) Determination of paclitaxel in human plasma by UPLC-MS-MS. J Chromatogr Sci 46:220–224. https://doi.org/10.1093/chromsci/46.3.220
Article
CAS
PubMed
Google Scholar
Goldwirt L, Lemaitre F, Zahr N, Farinotti R, Fernandez C (2012) A new UPLC-MS/MS method for the determination of irinotecan and 7-ethyl-10-hydroxycamptothecin (SN-38) in mice: application to plasma and brain pharmacokinetics. J Pharm Biomed Anal 66:325–333. https://doi.org/10.1016/j.jpba.2012.04.003
Article
CAS
PubMed
Google Scholar
Ju P, Liu Z, Jiang Y, Zhao S, Zhang L, Zhang Y, Gu L, Tang X, Bi K, Chen X (2015) Determination of a novel anticancer c-Met inhibitor LS-177 in rat plasma and tissues with a validated UPLC-MS/MS method: application to pharmacokinetics and tissue distribution study. Biomed Chromatogr 29:1103–1111. https://doi.org/10.1002/bmc.3397
Article
CAS
PubMed
Google Scholar
Lin H, Zhao Y, Men L, Yang M, Liu SY, Wang P, Tang X, Yu Z (2015) Development of a rapid and sensitive UPLC-MS/MS assay for the determination of TM-2 in beagle dog plasma and its application to a pharmacokinetic study. Biomed Chromatogr 29:110–114. https://doi.org/10.1002/bmc.3246
Article
CAS
PubMed
Google Scholar
Haandel LV, Becker ML, Williams TD, Leeder JS, Stobaugh JF (2011) Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC–MS/MS. Bioanalysis 3:2783–2796. https://doi.org/10.4155/bio.11.288
Article
CAS
PubMed
Google Scholar
Hubicka U, Żmudzki P, Talik P, Żuromska WB, Krzek J (2013) Photodegradation assessment of ciprofloxacin, moxifloxacin, norfloxacin and ofloxacin in the presence of excipients from tablets by UPLC-MS/MS and DSC. Chem Cent J7:133. https://doi.org/10.4155/bio.11.288
Goldwirt L, Zahr N, Farinotti R, Fernandez C (2013) Development of a new UPLC-MSMS method for the determination of temozolomide in mice: application to plasma pharmacokinetics and brain distribution study. Biomed Chromatogr 27:889–893. https://doi.org/10.1002/bmc.2877
Article
CAS
PubMed
Google Scholar
Wang S, Wu H, Geng P, Lin Y, Liu Z, Zhang L, Ma L, Zhou Y, Wang X, Wen C (2016) Pharmacokinetic study of dendrobine in rat plasma by ultra-performance liquid chromatography tandem mass spectrometry. Biomed Chromatogr 30:1145–1149. https://doi.org/10.1002/bmc.3641
Article
CAS
PubMed
Google Scholar
Li N, Han X, Du P, Song Y, Hu X, Yang S, Shi Y (2014) Development and validation of a UPLC-MS/MS assay for the quantification of simotinib in human plasma. Anal Bioanal Chem 406:1799–1805. https://doi.org/10.1007/s00216-013-7570-1
Article
CAS
PubMed
Google Scholar
Lin D, Qiao LM, Zhang N, Liu Y, Liu XS (2016) Simultaneous determination of nintedanib and its metabolite by UPLC–MS/MS in rat plasma and its application to a pharmacokinetic study. J Pharm Biomed Anal 117:173–177. https://doi.org/10.1016/j.jpba.2015.08.024
Article
CAS
PubMed
Google Scholar
CAO G, ZHANG Q, YANG X (2015) Determination of Letrozole in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study. Lat Am J Pharm 34:45–50
CAS
Google Scholar
Zhao AQ, Zhao JH, Zhang SQ, Pan YY, Huo XL (2016) Determination of parthenolide in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study. J Pharm Biomed Anal 119:99–103. https://doi.org/10.1016/j.jpba.2015.11.039
Article
CAS
PubMed
Google Scholar
Dahmane E, Mercier T, Zanolari B, Cruchon S, Guignard N, Buclin T, Leyvraz S, Zaman K, Csajka C, Decosterd LA (2010) An ultra performance liquid chromatography–tandem MS assay for tamoxifen metabolites profiling in plasma: first evidence of 4′-hydroxylated metabolites in breast cancer patients. J Chromatogr B 878:3402–3414. https://doi.org/10.1016/j.jchromb.2010.10.027
Article
CAS
Google Scholar
Yang F, Wang H, Hu P, Jiang J (2014) Validation of an UPLC–MS-MS method for quantitative analysis of vincristine in human urine after intravenous administration of vincristine sulfate liposome injection. J Chromatogr Sci 53:974–978. https://doi.org/10.1093/chromsci/bmu164
Article
CAS
PubMed
Google Scholar
Yang S, Qin F, Wang D, Li N, Li F, Xiong Z (2012) Determination of palonosetron in human plasma by ultra performance liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study. J Pharm Biomed Anal 57:13–18. https://doi.org/10.1016/j.jpba.2011.08.038
Article
CAS
PubMed
Google Scholar
Zhang WM, Li RF, Qiu JF, Zhang ZY, Wang HB, Bian L, Lei JH (2015) Determination of kurarinone in rat plasma by UPLC–MS/MS. J Chromatogr B 986:31–34. https://doi.org/10.1016/j.jchromb.2015.02.005
Article
CAS
Google Scholar
Liu H, Xu H, Song W, Zhang Y, Yu S, Huang X (2016) Validated UPLC/MS/MS assay for quantitative bioanalysis of elbasvir in rat plasma and application to pharmacokinetic study. J Chromatogr B 1015:150–156. https://doi.org/10.1016/j.jchromb.2016.02.025
Article
CAS
Google Scholar
Rezk MR, Bendas ER, Basalious EB, Karim IA (2016) Development and validation of sensitive and rapid UPLC–MS/MS method for quantitative determination of daclatasvir in human plasma: application to a bioequivalence study. J Pharm Biomed Anal 128:61–66. https://doi.org/10.1016/j.jpba.2016.05.016
Article
CAS
PubMed
Google Scholar
Shi X, Zhu D, Lou J, Zhu B, Hu AR, Gan D (2015) Evaluation of a rapid method for the simultaneous quantification of ribavirin, sofosbuvir and its metabolite in rat plasma by UPLC–MS/MS. J Chromatogr B 1002:353–357. https://doi.org/10.1016/j.jchromb.2015.08.038
Article
CAS
Google Scholar
Mishra T, Shrivastav PS (2014) Validation of simultaneous quantitative method of HIV protease inhibitors atazanavir, darunavir and ritonavir in human plasma by UPLC-MS/MS. Sci World J:1–12. https://doi.org/10.1155/2014/482693
Li TX, Chu CS, Zhu JY, Yang TY, Zhang J, Hu YT, Yang XH (2016) A rapid UPLC-MS/MS method for the determination of oleanolic acid in rat plasma and liver tissue: application to plasma and liver pharmacokinetics. Biomed Chromatogr 30:520–527. https://doi.org/10.1002/bmc.3577
Article
CAS
PubMed
Google Scholar
Jiménez GM, Contreras-Zavala L, Maggi-Castellanos M, Ángeles-Moreno AP, García-González A (2012) Development of a method by UPLC–MS/MS for the quantification of tizoxanide in human plasma and its pharmacokinetic application. Bioanalysis 4:909–917. https://doi.org/10.4155/bio.12.41
Article
CAS
Google Scholar
Wang Z, Huang CK, Sun W, Xiao C, Wang ZS (2015) UPLC-MS/MS determination of voriconazole in human plasma and its application to a pharmacokinetic study. Biomed Chromatogr 29:188–193. https://doi.org/10.1002/bmc.3257
Article
CAS
PubMed
Google Scholar
Al-Quadeib BT, Radwan MA, Siller L, Mutch E, Horrocks B, Wright M, Alshaer A (2014) Therapeutic monitoring of amphotericin B in Saudi ICU patients using UPLC MS/MS assay. Biomed Chromatogr 28:1652–1659. https://doi.org/10.1002/bmc.3198
Article
CAS
PubMed
Google Scholar
Decosterd LA, Rochat B, Pesse B, Mercier T, Tissot F, Widmer N, Bille J, Calandra T, Zanolari B, Marchetti O (2010) Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspofungin. Antimicrob Agents Chemother 54:5303–5315. https://doi.org/10.1128/AAC.00404-10
Article
CAS
PubMed
PubMed Central
Google Scholar
Rochat B, Pascual A, Pesse B, Lamoth F, Sanglard D, Decosterd LA, Bille J, Marchetti O (2010) Ultra-performance liquid chromatography mass spectrometry and sensitive bioassay methods for quantification of posaconazole plasma concentrations after oral dosing. Antimicrob Agents Chemother 54:5074–5081. https://doi.org/10.1128/AAC.00022-10
Article
CAS
PubMed
PubMed Central
Google Scholar
Abdelbary G, Nebsen M (2013) Application of a novel UPLC–MS/MS method for the pharmacokinetic/bioequivalence determination of atorvastatin and ezetimibe in human plasma. J Pharm Res 7:24–32. https://doi.org/10.1016/j.jopr.2013.01.010
Article
CAS
Google Scholar
Patel DP, Sharma P, Sanyal M, Singhal P, Shrivastav PS (2013) UPLC-MS/MS assay for the simultaneous quantification of carvedilol and its active metabolite 4′-hydroxyphenyl carvedilol in human plasma to support a bioequivalence study in healthy volunteers. Biomed Chromatogr 27:974–986. https://doi.org/10.1002/bmc.2889
Article
CAS
PubMed
Google Scholar
Zoerner AA, Schroeder C, Kayacelebi AA, Suchy MT, Gutzki FM, Stichtenoth DO, Tank J, Jordan J, Tsikas D (2013) A validated, rapid UPLC–MS/MS method for simultaneous ivabradine, reboxetine, and metoprolol analysis in human plasma and its application to clinical trial samples. J Chromatogr B 927:105–111. https://doi.org/10.1016/j.jchromb.2013.01.016
Article
CAS
Google Scholar
Pidpruzhnykov YV, Sabko EV, Iurchenko VV, Zupanets IA (2012) UPLC-MS/MS method for bioequivalence study of oral drugs of Meldonium. Biomed Chromatogr 26:599–605. https://doi.org/10.1002/bmc.1703
Article
CAS
PubMed
Google Scholar
Singh B, Lokhandae RS, Dwivedi A, Sharma S, Dubey N (2014) Improved simultaneous quantitation of candesartan and hydrochlorthiazide in human plasma by UPLC–MS/MS and its application in bioequivalence studies. J Pharm Anal 4:144–152
Article
CAS
PubMed
Google Scholar
Al-Dirbashi OY, Aboul-Enein HY, Jacob M, Al-Qahtani K, Rashed MS (2016) UPLC-MS/MS determination of doxazosine in human plasma. Anal Bioanal Chem 38:1439–1443. https://doi.org/10.1007/s00216-006-0553-8
Article
CAS
Google Scholar
Kalovidouris M, Michalea S, Robola N, Koutsopoulou M, Panderi I (2006) Ultra-performance liquid chromatography/tandem mass spectrometry method for the determination of lercanidipine in human plasma. Rapid Commun Mass Spectrom 20:2939–2946
Article
CAS
PubMed
Google Scholar
Ebeid MW, Elkady EF, El-Zaher AA, El-Bagary RI, Patonay G (2015) Simultaneous Determination of Aliskiren Hemifumarate, Amlodipine Besylate and Hydrochlorothiazide in Spiked Human Plasma Using UPLC-MS/MS. J Chromatogr Sci 53:178–1184. https://doi.org/10.1093/chromsci/bmu213
Article
CAS
Google Scholar
Wani TA, Zargar S (2015) New ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of irbesartan in human plasma. J Food Drug Anal 23:569–576. https://doi.org/10.1016/j.jfda.2015.02.008
Article
CAS
PubMed
Google Scholar
Rezk MR, Badr KA (2014) Development, optimization and validation of a highly sensitive UPLC–ESI-MS/MS method for simultaneous quantification of amlodipine, benazeprile and benazeprilat in human plasma: application to a bioequivalence study. J Pharm Biomed Anal 98:1–8. https://doi.org/10.1016/j.jpba.2014.05.005
Article
CAS
PubMed
Google Scholar
Prajapati ST, Patel PK, Chauhan VB, Patel CN, Patel M (2011) Development and validation of the liquid chromatography-tandem mass spectrometry method for quantitative estimation of candesartan from human plasma. Pharm Methods 2:130–134. https://doi.org/10.4103/2229-4708.84460
Article
PubMed
PubMed Central
Google Scholar
Favreto WAJ, Pugens Pinto AM, Manfio JL, Fiametti KG, Percio MF, Santos MBD (2012) Development and validation of a UPLC-ESI-MS/MS method for the determination of N-butylscopolamine in human plasma: application to a bioequivalence study. Drug Test Anal 4:215–221. https://doi.org/10.1002/dta.40
Article
CAS
PubMed
Google Scholar
Bae SK, Kang MJ, Yeo CW, Kim MJ, Shon JH, Liu KH, Shin JG (2008) Simultaneous determination of udenafil and its active metabolite, DA-8164, in human plasma and urine using ultra-performance liquid chromatography–tandem mass spectrometry: application to a pharmacokinetic study. Biomed Chromatogr 22:939–946. https://doi.org/10.1002/bmc.1011
Article
CAS
PubMed
Google Scholar
Lin X, Zhang Y, Cui Y, Wang L, Wang J, Tang X (2009) Determination of alprostadil in rat plasma by ultra performance liquid chromatography–electrospray ionization–tandem mass spectrometry after intravenous administration. J Pharm Biomed Anal 49:983–988. https://doi.org/10.1016/j.jpba.2009.01.019
Article
CAS
PubMed
Google Scholar
Kumbhar AB, Galgatte UC, Warkad S, Santhakumari B (2013) Development and validation of a sensitive bioanalytical method for the determination of sumatriptan in rat plasma by UPLC-MS. Int J Pharm Pharm Sci 5:78–82
CAS
Google Scholar
Liang L, Wan S, Xiao J, Zhang J, Gu M (2011) Rapid UPLC–MS/MS method for the determination of sufentanil in human plasma and its application in target-controlled infusion system. J Pharm Biomed Anal 54:838–844. https://doi.org/10.1016/j.jpba.2010.11.016
Article
CAS
PubMed
Google Scholar
Vuppala K, Boddu SP, Furr EB, McCurdy (2011) A Simple, sensitive, high-throughput method for the quantification of mitragynine in rat plasma using UPLC-MS and its application to an intravenous pharmacokinetic study. Chromatographia 74:703–710. https://doi.org/10.1007/s10337-011-2128-x
Article
CAS
Google Scholar
Hillewaert V, Pusecker K, Sips L, Verhaeghe T, Vries RD, Langhans M, Terlinden R, Timmerman P (2015) Determination of tapentadol and tapentadol-O-glucuronide in human serum samples by UPLC–MS/MS. J Chromatogr B 981:40–47. https://doi.org/10.1016/j.jchromb.2014.12.013
Article
CAS
Google Scholar
Inoue K, Sakamoto T, Fujita Y, Yoshizawa S, Tomita M, Min JZK, Todoroki K, Sobue T, Toyo'oka (2013) Development of a stable isotope dilution UPLC-MS/MS method for quantification of dexmedetomidine in a small amount of human plasma. Biomed Chromatogr 27: 853-858. doi:https://doi.org/10.1002/bmc.2870.
Huang PW, Liu HT, Hsiong CH, Pao LH, Lu CC, Ho ST, Hu OYP (2013) Simultaneous determination of nalbuphine and its prodrugsebacolydinalbuphine ester in human plasma by ultra-performance liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic study in humans. Biomed Chromatogr 27:831–837. https://doi.org/10.1002/bmc.2867
Article
CAS
PubMed
Google Scholar
Lüthi G, Blangy V, Eap CB, Ansermot N (2013) Buprenorphine and norbuprenorphine quantification in human plasma by simple protein precipitation and ultra-high performance liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal 77:1–8. https://doi.org/10.1016/j.jpba.2012.12.023
Article
CAS
PubMed
Google Scholar
Licea-Perez H, Wang S, Szapacs ME, Yang E (2008) Development of a highly sensitive and selective UPLC/MS/MS method for the simultaneous determination of testosterone and 5α-dihydrotestosterone in human serum to support testosterone replacement therapy for hypogonadism. Steroids 73:60–610. https://doi.org/10.1016/j.steroids.2008.01.018
Article
CAS
Google Scholar
Liu H, Yang M, Wu P, Guan J, Men L, Lin H, Tang X, Zhao Y, Yu Z (2015) Simultaneous determination of triamcinolone acetonidepalmitate and triamcinolone acetonide in beagle dog plasma by UPLC-MS/MS and its application to a long-term pharmacokinetic study of triamcinolone acetonidepalmitate lipid emulsion injection. J Pharm Biomed Anal 104:105–111. https://doi.org/10.1016/j.jpba.2014.11.028
Article
CAS
PubMed
Google Scholar
Leveques A, Actis-Goretta L, Rein MJ, Williamson G, Dionisi F, Giuffrida F (2012) UPLC–MS/MS quantification of total hesperetin and hesperetin enantiomers in biological matrices. J Pharm Biomed Anal 57:1–6. https://doi.org/10.1016/j.jpba.2014.11.028
Article
CAS
PubMed
Google Scholar
Wong KC, Law MC, Wong MS, Chan TH (2014) Development of a UPLC–MS/MS bioanalytical method for the pharmacokinetic study of (−)-epiafzelechin, a flavan-3-ol with osteoprotective activity, in C57BL/6J mice. J Chromatogr B 967:162–167. https://doi.org/10.1016/j.jchromb.2014.07.028
Article
CAS
Google Scholar
Mano Y, Ishii T, Hotta K, Kusano K (2015) Validation of a UPLC–MS/MS method for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human plasma. J Chromatogr B 998:31–39. https://doi.org/10.1016/j.jchromb.2015.06.023
Article
CAS
Google Scholar
Li X, Xiong Z, Lu S, Zhang Y, Li F (2010) Pharmacokinetics of naringin and its metabolite naringenin in rats after oral administration of RhizomaDrynariae extract assayed by UPLC-MS/MS. Chin J Nat Med 8:40–46. https://doi.org/10.3724/SP.J.1009.2010.00040
Article
CAS
Google Scholar
Szeitz A, Edginton AN, Peng HT, Cheung B, Riggs KW A validated enantioselective assay for the determination of ibuprofen in human plasma using ultra performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS). Am J Anal Chem 2(210):47–58. https://doi.org/10.4236/ajac.2010.12007
Zhang WM, Li RM, Sun M, Hu DM, Qiu JE, Yan YH (2014) UPLC–MS/MS method for determination of avicularin in rat plasma and its application to a pharmacokinetic study. J Chromatogr B 965:107–111. https://doi.org/10.1016/j.jchromb.2014.06.015
Article
CAS
Google Scholar
Wen C, Wang S, Huang X, Liu Z, Lin Y, Yang S, Ma J, Zhou Y, Wang X (2005) Determination and validation of hupehenine in rat plasma by UPLC-MS/MS and its application to pharmacokinetic study. Biomed Chromatogr 29:1805–1810. https://doi.org/10.1002/bmc.3499
Article
CAS
Google Scholar
He X, Zhang Y, Gao H, Li K, Zhang Y, Sun L, Tao G (2016) Simultaneous quantification of picfeltarraenins IA and IB in rat plasma by UPLC–MS/MS: application to a pharmacokinetic study. J Pharm Biomed Anal 120:32–37. https://doi.org/10.1016/j.jpba.2015.11.031
Article
CAS
PubMed
Google Scholar
Cui Y, Lin X, Guan TT, Zhang Y, Tang X (2010) A new rapid ultra-performance liquid chromatography method for the pharmacokinetic and bioavailability study of diclofenac sodium aqueous injection and lipid microsphere injection in rats. Biomed Chromatogr 24:406–412. https://doi.org/10.1002/bmc.130.
Article
CAS
PubMed
Google Scholar
Patel DP, Sharma P, Patel BM, Sanyal M, Singhal P, Shrivastav PS (2013) Analysis of 21-hydroxy deflazacort in human plasma by UPLC–MS/MS: Application to a bioequivalence study in healthy volunteers. J Pharm Biomed Anal 85:213–217. https://doi.org/10.1016/j.jpba.2013.07.035
Article
CAS
PubMed
Google Scholar
Qiu X, Lou D, Su D, Liu Z, Gao P, Zhang NS (2015) Simultaneous determination of acetaminophen and dihydrocodeine in human plasma by UPLC–MS/MS: Its pharmacokinetic application. J Chromatogr B 992:91–95. https://doi.org/10.1016/j.jchromb.2015.04.031
Article
CAS
Google Scholar
Qiu X, Zheng SL, Wang Y, Wang R, Ye L (2014) A Rapid and Simple UPLC–MS-MS Method for Determination of Glipizide in Human Plasma and Its Application to Bioequivalence Study. J Chromatogr Sci 53:85–89. https://doi.org/10.1093/chromsci/bmu023
Article
CAS
PubMed
Google Scholar
Cai S, Huo T, Li N, Xiong Z, Li F (2009) Lysophosphatidylcholine—biomarker of metformin action: studied using UPLC/MS/MS. Biomed Chromatogr 23:782–786. https://doi.org/10.1002/bmc.1185
Article
CAS
PubMed
Google Scholar
Jain R, Lukram O, Dwivedi A (2011) Ultra-performance liquid chromatography electrospray ionization–tandem mass spectrometry method for the estimation of miglitol in human plasma using metformin as the internal standard. Drug Test Anal. 3:255–262
Article
CAS
PubMed
Google Scholar
Zhang JF, Sha CF, Sun Y, Gai YY, Sun JY, Han JB, Shao X, Sha CN, Li YX, Liu WH (2013) Ultra-high-performance liquid chromatography for the determination of exenatide in monkey plasma by tandem quadrupole mass spectrometry. J Pharm Anal 3:235–240. https://doi.org/10.1016/j.jpha.2012.12.007
Article
CAS
PubMed
Google Scholar
Gu EM, Huang C, Liang B, Yuan L, Lan T, Hu G, Zhou H (2015) An UPLC–MS/MS method for the quantitation of vortioxetine in rat plasma: application to a pharmacokinetic study. J Chromatogr B 997:70–74. https://doi.org/10.1016/j.jchromb.2015.05.010
Article
CAS
Google Scholar
Denooz R, Mercerolle M, Lachâtre G, Charlier C (2010) Ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of bupropion and its main metabolites in human whole blood. J Anal Toxicol 34:280–286
Article
CAS
PubMed
Google Scholar
Qin F, Li N, Qin T, Zhang Y, Li F (2010) Simultaneous quantification of venlafaxine and O-desmethylvenlafaxine in human plasma by ultra performance liquid chromatography–tandem mass spectrometry and its application in a pharmacokinetic study. J Chromatogr B. 878:689–694. https://doi.org/10.1016/j.jchromb.2010.01.007
Article
CAS
Google Scholar
Bhatt M, Shah S (2010) Solid-phase extraction and analysis of paroxetine in human plasma by ultra-performance liquid chromatography–electrospray ionization mass spectrometry. Biomed Chromatogr 24:209–215. https://doi.org/10.1002/bmc.1275.
Article
CAS
PubMed
Google Scholar
Karinen R, Vindenes V, Hasvold I, Olsen KM, Christophersen AS, Oiestad E (2015) Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases. Drug Test Anal 7:634–644
Article
CAS
PubMed
Google Scholar
Proença P, Franco JM, Mustra C, Monteiro C, Costa J, Real FC, Vieira DN (2013) UPLC-MS/MS determination in blood of a mixed-drug fatal intoxication: a case report. Forensic Sci Int 227:85–89. https://doi.org/10.1016/j.forsciint.2012.10.038
Article
CAS
PubMed
Google Scholar
Bhatt M, Shah S (2015) Rapid ultra-performance liquid chromatography-tandem mass spectrometry method for quantification of Oxcarbazepine and its metabolite in human plasma. Biomed Chromatogr 25:751–759
Article
Google Scholar
Marin SJ, Roberts M, Wood M, McMillin GA (2012) Sensitive UPLC–MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem andzopiclone in serum or plasma. J AnalToxicol 36:472–476. https://doi.org/10.1093/jat/bks059
Article
CAS
Google Scholar
Liang F, Terry AV, Bartlett MG (2012) Determination of aripiprazole in rat plasma and brain using ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Biomed Chromatogr 26:1325–1332. https://doi.org/10.1002/bmc.2698
Article
CAS
PubMed
Google Scholar
Junnotula V, Licea-Perez H (2013) Development and validation of a simple and sensitive method for quantification of levodopa and carbidopa in rat and monkey plasma using derivatization and UPLC–MS/MS. J Chromatogr B 926:47–53. https://doi.org/10.1016/j.jchromb.2013.03.004
Article
CAS
Google Scholar
Zhang Y, Tingley FD, Tseng E, Tella M, Yang X, Groeber E, Liu J, Li W, Schmidt CJ, Steenwyk R (2012) Development and validation of a sample stabilization strategy and a UPLC–MS/MS method for the simultaneous quantitation of acetylcholine (ACh), histamine (HA), and its metabolites in rat cerebrospinal fluid (CSF). J Chromatogr B 879:2023–2033. https://doi.org/10.1016/j.jchromb.2011.05.030
Article
CAS
Google Scholar
Chunduri RHB, Dannana GS (2016) Development and validation of a high throughput UPLC–MS/MS method for simultaneous quantification of esomeprazole, rabeprazole and levosulpiride in human plasma. J Pharm Anal 6:190–198
Article
PubMed
PubMed Central
Google Scholar
Baietto L, Calcagno A, Motta I, Baruffi K, Poretti V, Di PG, Bonora S, D'avolio A (2015) A UPLC-MS-MS method for the simultaneous quantification of first-line antituberculars in plasma and in PBMCs. J Antimicrob Chemother 70:2572–2575. https://doi.org/10.1093/jac/dkv148
Article
CAS
PubMed
Google Scholar
Hampel D, York ER, Allen LH (2012) Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC–MS/MS) for the rapid, simultaneous analysis of thiamin, riboflavin, flavin adenine dinucleotide, nicotinamide and pyridoxal in human milk. J Chromatogr B 903:7–13. https://doi.org/10.1016/j.jchromb.2012.06.024
Article
CAS
Google Scholar
Jacobs BA, Rosing H, Vries ND, Meulendijks D, Henricks LM, Schellens JH, Beijnen JH (2016) Development and validation of a rapid and sensitive UPLC–MS/MS method for determination of uracil and dihydrouracil in human plasma. J Pharm Biomed Anal 126:75–82. https://doi.org/10.1016/j.jpba.2016.04.039
Article
CAS
PubMed
Google Scholar
Upadhyay V, Trivedi V, Shah G, Yadav M, Shrivastav PS (2012) Rapid and sensitive UPLC–MS-MS determination of Tacrolimus in Wistar rats and human blood. J Chromatogr Sci 52:59–67. https://doi.org/10.1093/chromsci/bms205
Article
CAS
PubMed
Google Scholar
Cao S, Ni B, Feng L, Yin X, Dou H, Fu J, Lin J, Ni J (2014) Simultaneous Determination of Typhaneoside and Isorhamnetin-3-O-Neohesperidoside in rats after oral administration of pollen Typhae extract by UPLC–MS/MS. J Chromatogr Sci 53:866–871. https://doi.org/10.1093/chromsci/bmu132.
Article
PubMed
Google Scholar
Upadhyay V, Trivedi V, Shah G, Yadav M, Shrivastav PS (2014) Determination of mycophenolic acid in human plasma by ultra performance liquid chromatography tandem mass spectrometry. J Pharm Anal 4:205–216
Article
CAS
PubMed
Google Scholar
Radwan MA, Bawazeer GA, Aloudah NM, AlQuadeib BT, Aboul-Enein HY (2012) Determination of free and total warfarin concentrations in plasma using UPLC MS/MS and its application to a patient samples. BiomedChromatogr 26:6–11. https://doi.org/10.1002/bmc.1616
Article
CAS
Google Scholar
Yang X, Liu S, Sun J, Liu X, Sun Y, He Z (2009) UPLC for the determination of clopidogrel in dog plasma by tandem quadrupole MS: application to a pharmacokinetic study. Chromatographia 70:259–263. https://doi.org/10.1365/s10337-009-1109-9
Article
CAS
Google Scholar
Xiong Z, Sun X, Huo T, Li N, Zheng Y, Sun Y (2010) Development and validation of UPLC-MS/MS method for simultaneous determination of gestodene and ethinyl estradiol in rat plasma. Biomed Chromatogr 24:160–168. https://doi.org/10.1002/bmc.1265.
Article
CAS
PubMed
Google Scholar
Hu G, Xu RA, Dong YY, Wang YY, Yao WW, Chen ZC, Chen D, Bu T, Ge RS (2015) Simultaneous determination of liensinine, isoliensinine and neferine in rat plasma by UPLC–MS/MS and application of the technique to pharmacokinetic studies. J Ethno Pharmacol 163:94–98. https://doi.org/10.1016/j.jep.2015.01.020
Article
CAS
Google Scholar
Rodríguez OP, Zapata-Morales JR, Moratilla AE, León-Cabrero MDD, Roque IT, Urizar JP (2015) Determination of Pinaverium bromide in human plasma by a sensitive and robust UPLC–MS-MS method and application to a pharmacokinetic study in Mexican subjects. J Chromatogr Sci 53:1373–1378. https://doi.org/10.1093/chromsci/bmv027
Article
CAS
Google Scholar
Liu Z, Jiang M, Lu X, Qin F, Song Y, Wen J, Li F (2012) Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC–MS/MS and its application to a pharmacokinetic study after administration of Toddaliaasiatica extract. J Chromatogr B 891:102–108. https://doi.org/10.1016/j.jchromb.2012.02.022
Article
CAS
Google Scholar
Zoerner AA, Batkai S, Suchy MT, Gutzki FM, Engeli S, Jordan J, Tsikas D (2012) Simultaneous UPLC–MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. J Chromatogr B 883:161–171. https://doi.org/10.1016/j.jchromb.2011.06.025
Article
CAS
Google Scholar
Huang X, Su S, Cui W, Liu P, Duan JA, Guo J, Li Z, Shang E, Qian D, Huang Z (2014) Simultaneous determination of paeoniflorin, albiflorin, ferulic acid, tetrahydropalmatine, protopine, typhaneoside, senkyunolide I in Beagle dogs plasma by UPLC–MS/MS and its application to a pharmacokinetic study after Oral Administration of ShaofuZhuyu Decoction. J Chromatogr B 962:75–81. https://doi.org/10.1016/j.jchromb.2014.05.032
Article
CAS
Google Scholar
Liu Y, Li X, Yang C, Tai S, Zhang X, Liu G (2012) UPLC–MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats. J Chromatogr Sci 51:26–32. https://doi.org/10.1093/chromsci/bms100
Article
CAS
PubMed
Google Scholar
Colón RK, Martínez MA, Silva-Torres LA, Chavez-Arias C, Negrón MM, Conte-Miller MS, Oquendo JB (2012) Simultaneous determination of Xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC–MS-MS. J Anal Toxicol 36:319–326. https://doi.org/10.1093/jat/bks024
Article
CAS
Google Scholar
Ma J, Wang S, Zhang M, Zhang Q, Zhou Y, Lin C, Lin G, Wang X (2015) Simultaneous determination of bupropion, metroprolol, midazolam, phenacetin, omeprazole and tolbutamide in rat plasma by UPLC-MS/MS and its application to cytochrome P450 activity study in rats. Biomed Chromatogr 29:1203–1212. https://doi.org/10.1002/bmc.3409
Article
CAS
PubMed
Google Scholar
Chen X, Gu E, Wang S, Zheng X, Chen M, Wang L, Hu G, Cai JP, Zhou H (2015) Evaluation of the effects of Ketoconazole and Voriconazole on the pharmacokinetics of Oxcarbazepine and its main metabolite MHD in rats by UPLC–MS-MS. J Chromatogr Sci 541:334–342. https://doi.org/10.1093/chromsci/bmv146.
Article
Google Scholar
Wang Y, Wen J, Zheng W, Zhao L, Fu X, Wang Z, Xiong Z, Li F, Xiao W (2015) Simultaneous determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid and geniposide in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study after administration of Reduning injection. Biomed Chromatogr 29:68–74. https://doi.org/10.1002/bmc.3241
Article
CAS
PubMed
Google Scholar
Zhao J, Chen X, Wang C, Wang Y, Ma C, Li W, Bi K (2010) Simultaneous determination of Evodiamine and Rutaecarpine in rat plasma by UPLC-MS-MS and its application in a pharmacokinetics study. Chromatographia 72:187–191. https://doi.org/10.1365/s10337-010-1633-7
Article
CAS
Google Scholar
Qiu X, Zhao J, Wang Z, Xu Z, Xu RA (2014) Simultaneous determination of bosentan and glimepiride in human plasma by ultra performance liquid chromatography tandem mass spectrometry and its application to a pharmacokinetic study. J Pharm Biomed Anal 95:207–212. https://doi.org/10.1016/j.jpba.2014.03.011
Article
CAS
PubMed
Google Scholar
Li H, Xia X, Xue Y, Tang S, Xiao X, Li J, Shen J (2012) Simultaneous determination of amoxicillin and prednisolone in bovine milk using ultra-high performance liquid chromatography tandem mass spectrometry. J Chromatogr B 900:59–63. https://doi.org/10.1016/j.jchromb.2012.05.031
Article
CAS
Google Scholar
Li G, Yang F, Liu M, Su X, Zhao M, Zhao L (2016) Development and application of a UPLC-MS/MS method for simultaneous determination of fenofibric acid and berberine in rat plasma: application to the drug–drug pharmacokinetic interaction study of fenofibrate combined with berberine after oral administration in rats. Biomed Chromatogr 30:1075–1082. https://doi.org/10.1002/bmc.3652.
Article
CAS
PubMed
Google Scholar
Pan J, Zhang C, Zhang Z, Li G (2014) Review of online coupling of sample preparation techniques with liquid chromatography. Analytica chimica acta 815:1–15. https://doi.org/10.1016/j.aca.2014.01.017
Ludvigsson JW, Andersson T, Kjellberg V (2016) A new method to identify hydrolytic degradants in drug substances with UPLC-MS using 18O-labelled water. J Pharm Biomed Anal 122:9–15. https://doi.org/10.1016/j.jpba.2016.01.041
Article
CAS
Google Scholar
Otasevic B, Milovanović S, Zečević M, Golubović J, Protić A (2014) UPLC method for determination of moxonidine and its degradation products in active pharmaceutical ingredient and pharmaceutical dosage form. Chromatographia 1:109–118. https://doi.org/10.1007/s10337-013-2580-x
Article
CAS
Google Scholar
Wingert NR, dos Santos NO, Nunes MA, Gomes P, Müller EI, Flores EM, Steppe M (2016) Characterization of three main degradation products from novel oral anticoagulant rivaroxaban under stress conditions by UPLC-Q-TOF-MS/MS. J Pharm Biomed Anal 123:10–15. https://doi.org/10.1016/j.jpba.2016.01.053
Article
CAS
PubMed
Google Scholar
Hubicka U, Żmudzki P, Talik P, Żuromska-Witek B, Krzek J (2013) Photodegradation assessment of ciprofloxacin, moxifloxacin, norfloxacin and ofloxacin in the presence of excipients from tablets by UPLC-MS/MS and DSC. Chem Cent J 7:133. https://doi.org/10.1186/1752-153X-7-133
Article
CAS
PubMed
PubMed Central
Google Scholar
Mei MK, Du Z, Xu R, Chen Y, Zhang H, Qu S (2012) Photocatalytic degradation of hexazinone and its determination in water via UPLC–MS/MS. J Hazard Mater 221:100–108. https://doi.org/10.1016/j.jhazmat.2012.04.018
Article
CAS
PubMed
Google Scholar
Hubicka U, Żmudzki P, Żuromska-Witek B, Zajdel P, Pawłowski M, Krzek J (2012) Separation and characterization of ciprofloxacin, difloxacin, lomefloxacin, norfloxacin, and ofloxacin oxidation products under potassium permanganate treatment in acidic medium by UPLC-MS/MS. Talanta 109:91–100. https://doi.org/10.1016/j.talanta.2013.01.055
Article
CAS
Google Scholar
Siddiqui MR, Alothman ZA, Wabaidur SM (2014) Ultra performance liquid chromatography–mass spectrometric method for determination of ampicillin and characterization of its forced degradation products. J Chromatogr Sci 52:1273–1280
Article
CAS
Google Scholar
Reddy YK, Reddy GS, Veera KJ, Hotha KK (2012) A Stability Indicating UPLC Method for Finasteride and Its Related Impurities. Am J Anal Chem 3:737–745. https://doi.org/10.4236/ajac.2012.311098P
Article
Google Scholar
Hotha KK, Patel T, Roychowdhury S, Subramanian V (2015) Identification, synthesis, and characterization of unknown impurity in the famotidine powder for oral suspension due to excipient interaction by UPLC-MS/MS and NMR. J Liq Chromatogr Rela Technol 38:977–985. doi:org/https://doi.org/10.1080/10826076.2014.999201.
Rao DD, Satyanarayana NV, Reddy AM, Sait SS, Chakole D, Mukkanti K (2010) A validated stability-indicating UPLC method for desloratadine and its impurities in pharmaceutical dosage forms. J Pharm Biomed Anal 51:736–742. https://doi.org/10.1016/j.jpba.2009.09.016
Article
CAS
PubMed
Google Scholar
Mowaka S, Mohamed D (2015) Novel contribution to the simultaneous analysis of certain hypoglycemic drugs in the presence of their impurities and degradation products utilizing UPLC-MS/MS. RSC Adv 5:60467–60481. https://doi.org/10.1039/C5RA11448A
Article
CAS
Google Scholar
Liu C, Hua Z, Bai Y (2015) Classification of illicit heroin by UPLC–Q-TOF analysis of acidic and neutral manufacturing impurities. Forensic Sci Int 257:196–202. https://doi.org/10.1016/j.forsciint.2015.08.009
Article
CAS
PubMed
Google Scholar
Bapatu HR, Maram RK, Cho WH, Pasagadugula VBR (2016) QbD Approach method development for estimation of Dabigatran Etexilate along with its impurities and identification of degradants in capsule dosage form. Am J Anal Che 7:494–524. https://doi.org/10.4236/ajac.2016.76047
Article
CAS
Google Scholar
Reddy AVB, Venugopal N, Madhavi G, Reddy KG, Madhavi V (2013) A selective and sensitive UPLC–MS/MS approach for trace level quantification of four potential genotoxic impurities in zolmitriptan drug substance. J Pharm Biomed Anal 84:84–89. https://doi.org/10.1016/j.jpba.2013.05.047
Article
CAS
Google Scholar
Thomas JL, Lincoln D, McCord BR (2013) Separation and detection of smokeless powder additives by ultra performance liquid chromatography with tandem mass spectrometry (UPLC/MS/MS). J Forensic Sci 58:609–615. https://doi.org/10.1111/1556-4029.12096
Article
CAS
PubMed
Google Scholar
Koppala S, Panigrahi B, Raju SVN, Reddy KP, Reddy VR, Anireddy JS (2014) Development and validation of a simple, sensitive, selective and stability-indicating RP-UPLC Method for the quantitative determination of ritonavir and its related compounds. J Chromatogr Sci 53:662–675. https://doi.org/10.1093/chromsci/bmu097
Article
CAS
PubMed
Google Scholar
Ding M, Lu J, Zhao C, Zhang S, Zhao Y (2016) Determination of 25-OCH 3-PPD and the related substances by UPLC–MS/MS and their cytotoxic activity. J Chromatogr B 1022:274–280. https://doi.org/10.1016/j.jchromb.2016.04.031
Article
CAS
Google Scholar
Chrial columns. http://www.ymc.co.jp/en/columns/chiral_art/ Accessed 30 November 2018.
Baranowska I, Hejniak J, Magiera S (2016) Simultaneous Chiral Separation of Flavanone, Naringenin, and Hesperetin Enantiomers by RP-UHPLC-DAD. Chirality 28:147–152. https://doi.org/10.1002/chir.22559
Article
CAS
PubMed
Google Scholar
Baranowska I, Hejniak J, Magiera S (2016) Development and validation of a RP-UHPLC-ESI-MS/MS method for the chiral separation and determination of flavanone, naringenin and hesperetin enantiomers. Talanta 1(159):181–188. https://doi.org/10.1016/j.talanta.2016.06.020
Article
CAS
Google Scholar
Li L, Lurie IS (2015) Regioisomeric and enantiomeric analyses of 24 designer cathinones and phenethylamines using ultra high performance liquid chromatography and capillary electrophoresis with added cyclodextrins. Forensic Sci Int 1(254):148–157. https://doi.org/10.1016/j.forsciint.2015.06.026
Article
CAS
Google Scholar
Ramisetti NR, Arnipalli MS, Nimmu NV, Bondigalla R (2017) UHPLC determination of besifloxacin enantiomers on immobilized amylose tris (3, 5-dichlorophenylcarbamate) chiral stationary phase. Chromatographia 80:1509–1515. https://doi.org/10.1007/s10337-017-3346-7
Article
CAS
Google Scholar
Regalado EL, Schafer W, McClain R, Welch CJ (2013) Chromatographic resolution of closely related species: separation of warfarin and hydroxylated isomers. J Chromatogr A1 1314:266–275. https://doi.org/10.1016/j.chroma.2013.07.092
Article
CAS
Google Scholar
Regalado EL, Helmy R, Green MD, Welch CJ (2014) Chromatographic resolution of closely related species: drug metabolites and analogs. J Sep Sci 37:1094–1102. https://doi.org/10.1002/jssc.201400038
Article
CAS
PubMed
Google Scholar
Balaji N, Sultana S (2017) Reversed-phase UHPLC enantiomeric separation of rasagiline salts using a Chiralpak® AGP Column. Sci Pharm 85:26. https://doi.org/10.3390/scipharm85030026
Article
CAS
PubMed Central
Google Scholar
Yang J, Wang Y, Pan L, Li N, Lu X, Guan J, Cheng M, Li F (2009) Enantioselective determination of trantinterol in rat plasma by ultra performance liquid chromatography–electrospray ionization mass spectrometry after derivatization. Talanta 79:1204–1208. https://doi.org/10.1016/j.talanta.2009.03.036
Article
CAS
PubMed
Google Scholar
Wang G, Hsieh Y, Cheng KC, Morrison RA, Venkatraman S, Njoroge FG, Heimark L, Korfmacher WA (2007) Ultra-performance liquid chromatography/tandem mass spectrometric determination of diastereomers of SCH 503034 in monkey plasma. J Chromatogr B 852:92–100. https://doi.org/10.1016/j.jchromb.2006.12.038
Article
CAS
Google Scholar
Malati V, Reddy AR, Mukkanti K, Suryanarayana MV (2012) A novel reverse phase stability indicating RP-UPLC method for the quantitative determination of fifteen related substances in Ranolazine drug substance and drug product. Talanta 97:563–573. https://doi.org/10.1016/j.talanta.2012.03.067
Article
CAS
PubMed
Google Scholar
Raju TS, Kalyanaraman L, Reddy VV, Swamy PY (2012) Development and validation of an UPLC method for the rapid separation of positional isomers and potential impurities of rivastigmine hydrogen tartrate in drug substance and drug product. J Liq Chromatogr Relat Technol 35(7):896–911. https://doi.org/10.1080/10826076.2011.613143
Zhang Q, Wang D, Zhang M, Zhao Y, Yu Z (2017) The determination of 2-(2-hydroxypropanamido) benzoic acid enantiomers and their corresponding prodrugs in rat plasma by UHPLC–MS/MS and application to comparative pharmacokinetic study after a single oral dose. J Chromatogr B 1041:175–182. https://doi.org/10.1016/j.jchromb.2016.11.017
Article
CAS
Google Scholar
Jin H, Thangadurai TD, Jo SC, Jin D, Cui S, Lee YI (2012) On-line chiral analysis of benzylmercapturic acid and phenylmercapturic acid in human urine using UPLC-QToF mass spectrometry with the kinetic method. Microchem J 103:170–176. https://doi.org/10.1016/j.microc.2012.03.003
Article
CAS
Google Scholar
Reyes-Reyes ML, Roa-Morales G, Melgar-Fernández R, Reyes-Pérez H, Gómez-Oliván LM, Gonzalez-Rivas N, Bautista-Renedo J, Balderas-Hernández P (2015) Chiral recognition of abacavir enantiomers by (2-hydroxy) propyl-β-cyclodextrin: UHPLC, NMR and DFT studies. J InclPhenomMacrocyclChem 82:373–382. https://doi.org/10.1007/s10847-015-0499-6
Article
CAS
Google Scholar
Monfort N, Martínez L, Bergés R, Segura J, Ventura R (2015) Screening method for stimulants in urine by UHPLC-MS/MS: identification of isomeric compounds. Drug Test Anal 7:819–830. https://doi.org/10.1002/dta.1776
Article
CAS
PubMed
Google Scholar
Zhao J, Shin Y, Jin Y, Jeong KM, Lee J (2017) Determination of enantiomericvigabatrin by derivatization with diacetyl-L-tartaric anhydride followed by ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. J Chromatogr B 1040:199–207. https://doi.org/10.1016/j.jchromb.2016.11.016
Article
CAS
Google Scholar
Pan X, Dong F, Chen Z, Xu J, Liu X, Wu X, Zheng Y (2017) The application of chiral ultra-high-performance liquid chromatography tandem mass spectrometry to the separation of the zoxamide enantiomers and the study of enantioselective degradation process in agricultural plants. J Chromatogr A 1525:87–95. https://doi.org/10.1016/j.chroma.2017.10.016
Article
CAS
PubMed
Google Scholar